Autoimmune hepatitis complicated by adult‐onset Still's disease during treatment with tocilizumab: A case report from acute onset to recurrence

Abstract

Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology that usually affects young adults. 1 Spiking fever, arthritis, and evanescent rash are commonly observed during the course of the disease. Other frequently observed clinical features include sore throat, hepatosplenomegaly, lymphadenopathy, and serositis. 2 Adult-onset Still's disease is usually complicated by liver dysfunction. 3 However, cases of autoimmune hepatitis (AIH) complicated by AOSD are rare, and discerning the cause of liver dysfunction as AOSD or AIH is difficult. This was a very rare case that could be followed up from acute onset to recurrence of AIH complicated by AOSD. Herein, we report a case of AIH complicated by AOSD that was successfully diagnosed by a liver biopsy.