Autoimmune hepatitis in southern Israel: A 15‐year multicenter study

Abstract

The prevalence of AIH in Israel is quite similar to that of other European Caucasian populations, with a relatively long-term good prognosis, despite a low rate of response to immunosuppressive therapy.

Incidence and Characteristics of Autoimmune Hepatitis

“…14 Available adult data indicate an incidence varying from 0.67 to 2 cases per 100 000 people. [15][16][17] Ethnic background has been reported as a key factor in clinical presentation and outcomes for patients with AIH 18,19 ; however, this finding is not universal. 20 In the present national study, our primary aim was to determine the incidence of AIH in children and adolescents in Canada and to describe its clinical characteristics and natural history.…”

Childhood autoimmune hepatitis in a paediatric unit of a tertiary care hospital

“…The prevalence of AIH in Singapore was reported to be 4 cases per 100,000 children, (1) while the worldwide prevalence was reported to be 2-17 per 100,000 children. (2)(3)(4)(5) AIH results in the progressive destruction of hepatic parenchyma, which may subsequently develop into cirrhosis and hepatic failure if treatment is not initiated at an early stage.…”

Population-Based Prevalence, Incidence, and Disease Burden of Autoimmune Hepatitis in South Korea

“…The incidence and prevalence rates of AIH vary widely across different populations (Table 6). [1][2][3][4][5][6][7][8][9][10][11][12][13][14]16] The prevalence was highest in an Alaskan native population (42.9/100,000), modest in European and New Zealand populations (mainly Caucasians, 10.7-24.5/100,000), and low in populations from Singapore and Brunei (4-5.6/ 100,000). [1-6, 9, 10] The annual incidence rate was low in Taiwan and Israel (0.52-0.67/ 100,000) and relatively high in Europe (0.85-3/100,000).…”

“…Prevalence estimates range widely from 4 to 42.9 cases per 100,000 persons [1][2][3][4][5][6][7][8][9][10][11], and reported annual incidences range from 0.67 to 2.23 cases per 100,000 persons. [1,4,6,[8][9][10][11][12][13][14] The variable results may be attributed to differences in genetics, environmental factors, and study population or design, and these heterogeneous factors make it challenging to understand the global epidemiology and disease burden of AIH.…”