Autoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review

Bronz, Gabriel; Gianini, Jvan; Passi, Alberto G; Rizzi, Mattia; Bergmann, M; Milani, Gregorio P.; Lava, Sebastiano A. G.; Bianchetti, Mario G.; Beretta‐Piccoli, Benedetta Terziroli; Vanoni, Federica

doi:10.1016/j.jaut.2023.103002

Journal of Autoimmunity

2023

DOI: 10.1016/j.jaut.2023.103002

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Autoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review

Gabriel Bronz¹,

Jvan Gianini²,

Alberto G Passi³

et al.

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Cited by 2 publications

References 16 publications

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Accurate diagnosis of acute hemorrhagic edema of infancy: a French multicenter observational study

Leducq,

Maruani,

Bodemer

et al. 2023

Eur J Pediatr

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Accurate diagnosis of acute hemorrhagic edema of infancy: a French multicenter observational study

Leducq,

Maruani,

Bodemer

et al. 2023

Eur J Pediatr

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Acute hemorrhagic edema of infancy: 20‐year experience from an Italian tertiary referral center

Fiordelisi,

Soldovieri,

Pagnini

et al. 2024

Pediatric Dermatology

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PurposeData on acute hemorrhagic edema of infancy (AHEI) are derived from small case series or case reports. We report a 20‐year experience at a national referral center.MethodsWe performed a single‐center retrospective study including patients who were diagnosed with AHEI from January 1, 2004, to June 30, 2023.ResultsWe identified 21 patients (57.1% females) with a median age of 18 months (range 7–33 months). Thirteen (61.9%) patients were admitted to the pediatric ward, the remaining eight (38.1%) presented to the emergency department and were discharged for outpatient management. The median length of hospitalization was 5 days (range 3–9 days). Twenty patients (95.2%) had prodromal symptoms. The most common cutaneous findings were targetoid purpuric plaques. The lesions were most localized on the face (13, 61.9%) and on the upper limbs (18 patients, 85.7%). Sixteen (76%) patients presented with nonpitting and tender edema, localized on the feet (9/16, 56%) and hands (6/16, 37.5%). Systemic involvement was rare, and no patients experienced complications or sequelae. Twelve (57.1%) patients underwent infectious disease investigations, with positive results in only four (33.3%). None of the patients diagnosed after the SARS‐CoV‐2 outbreak (March 2020) had positive nasopharyngeal swabs for the virus. For the 13 patients who were admitted to the pediatric ward, the median length of hospitalization was five days (3–9 days).ConclusionsThe 21‐patient single‐center cohort of children affected by AHEI confirmed a generally benign course of AHEI, despite a 62% rate of hospitalization.

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Autoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review

Cited by 2 publications

References 16 publications

Accurate diagnosis of acute hemorrhagic edema of infancy: a French multicenter observational study

Accurate diagnosis of acute hemorrhagic edema of infancy: a French multicenter observational study

Acute hemorrhagic edema of infancy: 20‐year experience from an Italian tertiary referral center

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