Autoimmune pancreatitis: an adolescent case and review of literature

Blejter, Javier; Weller, Santiago; Pace, Rosina; Cusumano, Humberto; Giambini, Daniel

doi:10.1016/j.jpedsurg.2008.02.064

Cited by 29 publications

(20 citation statements)

References 29 publications

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“…As in other series, 2Y6,8 the results of our work are influenced by the incompleteness of the collected data because of the retrospective study design as well as the bias in patient selection, the experience of the clinicians in our center, and the lack of investigation for other etiologies, as a sphincter of Oddi dysfunction and autoimmune pancreatitis. 38,39 In conclusion, our data confirm that recurrent pancreatitis in pediatric age is a complex disease in which structural and genetic factors play a major role than the environment. 40 Early recognition of the etiology involved is important because it may favor a complete resolution of the disease (biliopancreatic malformations or gallstones) or prevent complications in other organs in late-onset CF patients.…”

Section: Discussionsupporting

confidence: 72%

The Etiology of Acute Recurrent Pancreatitis in Children

Lucidi¹,

Alghisi²,

Dall’Oglio³

et al. 2011

Pancreas

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Section: Discussionsupporting

confidence: 72%

The Etiology of Acute Recurrent Pancreatitis in Children

Lucidi¹,

Alghisi²,

Dall’Oglio³

et al. 2011

Pancreas

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“…The rare sclerosing variant of anaplastic large cell lymphoma can display ALK-1 reactivity in addition to smooth muscle actin but usually has histologic foci characteristic for anaplastic large cell lymphoma and expresses other markers, such as CD30, epithelial membrane antigen, granzyme, perforin, and TIA-1 [424,425]. The IgG4-related sclerosing lesions tend to occur in older adults, have a more diffusely infiltrative and less circumscribed growth pattern than IMT, contain a relatively large proportion of IgG4-positive plasma cells, and may display obliterative phlebitis [386,[426][427][428][429][430][431][432][433][434][435][436][437].…”

Section: Intermediate (Rarely Metastasizing) Fibroblastic-myofibroblamentioning

confidence: 99%

Fibroblastic and Myofibroblastic Tumors in Children and Adolescents

2012

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Fibroblastic and myofibroblastic tumors in children and adolescents are a relatively common group of soft tissue proliferations that range from reactive to hamartomatous to neoplastic, with a full spectrum of benign, intermediate, and malignant neoplasms. These lesions are diagnostically challenging because of morphologic and immunohistochemical overlap, despite significant clinical, genetic, and prognostic differences. The fibromatoses are a major subgroup, and all types of fibromatoses can occur in the 1st 2 decades of life. Intermediate and malignant fibroblastic-myofibroblastic tumors are an important group that includes variants of fibrosarcoma and other tumors with recurrent cytogenetic or molecular genetic abnormalities and low metastatic potential. Pathologic examination is enhanced by adjunct techniques, such as immunohistochemistry, cytogenetics, and molecular genetics, although morphology provides the ultimate criteria for a specific diagnosis. This article reviews the clinicopathologic features of fibroblastic and myofibroblastic tumors with an emphasis on the unique aspects of these neoplasms in children and adolescents, the use of diagnostic adjuncts, and differential diagnoses.

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“…The cancer risk from chronic pancreatitis and cystic fibrosis may become a bigger issue later as more of these patients survive into adulthood [44]. Other causes of chronic pancreatitis include inborn errors of metabolism, fibrosing pancreatitis, tropical pancreatitis, and autoimmune pancreatitis [45][46][47].…”

Section: Chronicmentioning

confidence: 99%

“…Autoimmune pancreatitis is rare in children [45]. Symptoms may vary, although obstructive jaundice is the most common presentation in adults.…”

Section: Chronicmentioning

confidence: 99%

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Pancreatic Disease in Children and Adolescents

Jolley

2010

Curr Gastroenterol Rep

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Many childhood pancreatic disorders are rare, although they can represent significant and potentially severe disease. The spectrum of disease is very broad, ranging from the complex and bizarre congenital anomalies to the more typical acquired causes (e.g., drug-induced pancreatitis or trauma injury). Genetics appears to play a major role in many childhood pancreas diseases, unlike adults where alcohol is a major factor. Nevertheless, there are similarities, and most of the disorders discussed here can be found in both the pediatric and adult age groups. Some of these disorders may be evolving and may be seen in both young and older patients. Newer imaging modalities and therapeutic endoscopy continue to be studied, although their ultimate role and utility in children has yet to be fully elucidated.

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Autoimmune pancreatitis: an adolescent case and review of literature

Cited by 29 publications

References 29 publications

The Etiology of Acute Recurrent Pancreatitis in Children

The Etiology of Acute Recurrent Pancreatitis in Children

Fibroblastic and Myofibroblastic Tumors in Children and Adolescents

Pancreatic Disease in Children and Adolescents

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