Autologous Blood Pleurodesis in Rats to Elucidate the Amounts of Blood Required for Reliable and Reproducible Results

Özpolat, Berkant; Gazyagci, Serkal; Gözübüyük, Alper; Ayva, Ebru Sebnem; Atinkaya, Cansel

doi:10.1016/j.jss.2009.01.027

Cited by 19 publications

(29 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is followed by subsequent inflammation and fibrinous pleuritis promoting formation of adhesions, whereas actual pleurodesis occurs in a later phase. 8,25 In this case series, all cats developed continuous pneumothorax following diaphragmatic herniorrhaphy. Continuous pneumothorax following diaphragmatic herniorrhaphy may be attributed to pulmonary trauma from the inciting cause of DH, intraoperatively from breakdown of pulmonary adhesions, iatrogenically from blind chest tube placement or transdiaphragmatic thoracocentesis, or associated with re-expansion injury.…”

Section: Discussionmentioning

confidence: 80%

Allogenic blood patch pleurodesis for continuous pneumothorax in three cats

Bersenas

Hoddinott

2020

Journal of Feline Medicine and Surgery Open Reports

View full text Add to dashboard Cite

Case series summary Following diaphragmatic herniorrhaphy, three cats developed a continuous pneumothorax. All three cats required continuous suction to evacuate air from the thoracic cavity. Despite continuous suction, the pneumothorax persisted for all cats and blood patch pleurodesis (BPP) was performed using blood donor cats. All three cats had resolution of their pneumothorax within 24 h of BPP. Relevance and novel information This is the first report of BPP used in feline patients. More recently autologous BPP has been reported for use in dogs and humans, with a reportedly high success rate. BPP may allow timely resolution of continuous pneumothorax in cats and provide an alternative treatment option to prolonged medical management or surgical intervention. Allogenic blood from a donor cat may be necessitated in feline BPP when cardiovascular instability is appreciated in these small patients.

show abstract

Section: Discussionmentioning

confidence: 80%

Allogenic blood patch pleurodesis for continuous pneumothorax in three cats

Bersenas

Hoddinott

2020

Journal of Feline Medicine and Surgery Open Reports

View full text Add to dashboard Cite

show abstract

“…Most other series have reported using ABP between five and nine days after conservative treatment. [13][14][15] Although some authors have waited up to five weeks 6 before applying ABP, it is intuitive that the longer the chest drain has been in-situ, the greater the likelihood of colonization of the chest tube with bacteria. This could potentially exacerbate chances of infection in the pleural space when performing ABP.…”

Section: Discussionmentioning

confidence: 99%

“…10 The success of ABP in our series is considerably lower than in many reported series. 5,13,14 It is possible to explain when we look more closely to the specific aspects of our methodology and the nature of previous reports. Almost all previous reports are severely limited by their small sample size.…”

Section: Discussionmentioning

confidence: 99%

Autologous blood patching in the management of broncho-pleural fistula in spontaneous pneumothorax

Thapa

Sapkota

Sayami

2017

J. Soc. Surg. Nepal

View full text Add to dashboard Cite

show abstract

“…From animal experimental studies [Ozpolat et al 2010;Mitchem et al 1999], autologous blood had dual mechanism effects on PAL and created pleurodesis. Firstly, the formation of a clot (blood patch effect) and subsequently induced pleural irritation and inflammation, leading to the formation of pleural adhesions (fibrinous pleuritis).…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety profile of autologous blood versus tetracycline pleurodesis for malignant pleural effusion

Keeratichananont

Limthon

Keeratichananont

2015

Ther Adv Respir Dis

View full text Add to dashboard Cite

Objectives: Autologous blood pleurodesis (ABP) is used for the treatment of pneumothorax with a good efficacy. The aim of this study is to determine the efficacy and safety of ABP in the treatment of malignant pleural effusion (MPE). Methods: A prospective study was conducted at Songklanagarind Hospital, Thailand. Symptomatic MPE patients were randomized to receive pleurodesis with either autologous blood or tetracycline. In the ABP group, 100 ml of autologous venous blood was instilled via chest tube followed by 50 ml of sterile normal saline (NSS). In the tetracycline group, 20 ml of 1% lidocaine diluted in 30 ml NSS was instilled followed by 1 g of tetracycline diluted in 100 ml of NSS. The chest tube was clamped for 2 hours, then reconnected to suction and removed. Pleurodesis effectiveness was evaluated according to Paladine's criteria and adverse events were recorded. Results: A total of 48 symptomatic MPE patients were recruited. Of these, 24 cases were randomized to receive ABP and 24 cases received tetracycline. There was no difference between the two groups in baseline characteristics. The overall success rate of pleurodesis was the same in both the autologous blood group and the tetracycline group (83.4% versus 87.5%, p = 0.36). In the ABP group, the pain score and fever were significantly lower (8.3% versus 29.1%, p = 0.003) and there was a small percentage of cases that needed analgesia (4.2% versus 75%, p < 0.001); no serious events occurred. Conclusions:: ABP was as effective as tetracycline in the treatment of MPE. ABP produced less pain and fever, and could shorten the hospital stay.

show abstract

Autologous Blood Pleurodesis in Rats to Elucidate the Amounts of Blood Required for Reliable and Reproducible Results

Cited by 19 publications

References 14 publications

Allogenic blood patch pleurodesis for continuous pneumothorax in three cats

Allogenic blood patch pleurodesis for continuous pneumothorax in three cats

Autologous blood patching in the management of broncho-pleural fistula in spontaneous pneumothorax

Efficacy and safety profile of autologous blood versus tetracycline pleurodesis for malignant pleural effusion

Contact Info

Product

Resources

About