Autologous Fat Transfer for Facial Augmentation and Regeneration

Clauser, Luigi; Lucchi, Antonio; Tocco-Tussardi, Ilaria; Gardin, Chiara; Zavan, Barbara

doi:10.1016/j.cxom.2017.10.002

Cited by 17 publications

(24 citation statements)

References 63 publications

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“…Bologna -Italy). The tunnelings are performed in the subcutaneous tissue adjacent to the dermis; this layer has been proven to hold more mesenchymal and vascular stem cells [8,9]. Once the adipose tissue is harvested, it is transferred into 1ml luer lock syringes.…”

Section: Microfat a Preparationmentioning

confidence: 99%

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Hair Transplantation in Cicatricial Alopecia: The Role of Autologous Fat Transfer

Tesauro¹,

Trivisonno²,

Gennai³

et al. 2020

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Aim: The purpose of this article is to prove the importance of autologous fat transfer (AFT) in scarring alopecia. Methods: We present a complete clinical report of 21 cases treated with a combined procedure of AFT and hair transplantation (HT) done in the last three years. Results: The main findings of this study are the constant, early and more predictable hair regrowth after the hair transplant done on a pre-treated scarring alopecia. Conclusion: Tissue regeneration through AFT can significantly improve hair growth in the area of scarring alopecia, underlining, once again, the tremendous potential of this approach. Future studies may need to be carried out.

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Section: Microfat a Preparationmentioning

confidence: 99%

“…The lipostructure procedure is performed under local, local assisted or general anaesthesia using Dr. Coleman's technique [12,13]. In the most penetrable tissues a cannula has been used for fat positioning, in other tissues needles have been used for the same reasons described above.…”

Section: Lipostructurementioning

confidence: 99%

Hair Transplantation in Cicatricial Alopecia: The Role of Autologous Fat Transfer

Tesauro¹,

Trivisonno²,

Gennai³

et al. 2020

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“…Bologna -Italy) (Figure 1) [27][28][29][30][31]. The guide is addressed to standardize the procedure, to guarantee tunneling are performed in the subcutaneous tissue adjacent to the dermis; this layer has been proven to hold more mesenchymal and vascular stem cells (Figure 2) [32,33]. Once the adipose tissue is harvested, it is gently washed.…”

Section: Procedures Analysismentioning

confidence: 99%

Infranatant Portion of Microfragmented Adipose Tissue: A Promising Source of SVF for the Management of Androgenetic Alopecia

Gennai¹,

Tesauro²,

Colli³

et al. 2021

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Aim: The purpose of this article is to prove the possibility to transfer a good amount of cells of the SVF (and ADSCs) in the infranatant portion of microfragmented adipose tissue. Method: The adipose tissue harvesting procedure is performed under local anaesthesia. The adipose tissue was harvested with a 2 mm diameter microperforated cannula with 1 mm side port holes, mounted inside the special patented guide. Both cannula and guide are included in the SEFFIHAIR™ medical device. Once the adipose tissue is harvested, it is gently washed, and it was divided in two specimens: (EMU) the tissue was emulsified with 20 passages from one syringe to another and (CTRL) the tissue didn’t undergo any emulsification. Results: The emulsification procedure liberated alive and proliferating cells and we observed that the specimens derived with a 1 mm side port hole cannula and then emulsified (EMU) showed a higher number of cells in the infranatant part compared to the one derived from the control tissue without any (1 EMU vs. 1EMU infra). Conclusion: The use of microcannulas, in combination with a mechanical digestion by an emulsification procedure and centrifuge, could ease SVF cells isolation for regenerative treatment and could also be performed in a medical facility.

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“…Studies have found that fat contains more mesenchymal stem cells than any other human tissue, which can explain why fat transfer has been observed to also improve the quality of the overlying skin at the donor site. 1 Maxillofacial surgeons have historically used fat transfer for the obliteration of frontal sinuses and the nasofrontal ducts after trauma. 3 AFT can also be used for delayed reconstruction of traumatic injuries such as dog bites with significant tissue avulsion or in severe burns, when contracture of skin and damage to underlying tissue is present.…”

Section: Possible Complicationsmentioning

confidence: 99%