Autologous Fat Transfer in a Patient with Lupus Erythematosus Profundus

Yoon, Jimi; Kim, Hwa Mi; Kim, Tae‐Heung; Kim, Chung-Won; Sun, Young-Woo; Yoon, Tae‐Jin

doi:10.1159/000343469

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…suggested that the autologous fat transfer is a good choice to correct face atrophic lesions in patients with lupus erythematosus. Unquestionable advantages of this method are that the material used is patients’ own tissue (biocompatible), it has no allergic reaction and is easy to harvest [ 15 ]. A similar treatment path was introduced in the first described patient.…”

Section: Discussionmentioning

confidence: 99%

Surgical treatment of skin lesions in lupus erythematosus

Lewandowicz

Zieliński

Iljin

et al. 2014

pdia

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Lipodystrophies are a wide group of diseases with various etiology, mainly genetic, metabolic or autoimmune. The treatment of these diseases is chronic and not always effective. Major concerns for patients with lipodystrophies are also esthetic defects, especially deformities in the face, neck and upper limbs. There are many surgical methods that can be used to improve patient's appearance like fillers, autologous fat transfer and skin flaps. The aim of this paper is to present and discuss surgical techniques used for correction of lipoatrophy and other skin lesions present in lupus erythematosus. In the first presented patient, lipodermal grafts were performed in two stages (first – to both zygomatic areas, the second – to both nasolabial folds). Moreover, the patient was qualified for arm scar plasty. Deepithelialized skin in the affected area was covered with advanced local skin flaps. In the second patient, an extensive scarring lesion on the scalp was excised and the defect was closed with an expanded scalp flap. Patients with lipodystrophies may require aesthetic surgical procedures to improve their appearance. In patients with lupus erythematosus, autologous fat graft in the face area seems to be a safe and effective method of refilling the volume of atrophic tissues. On the basis of our experience, it is worth emphasizing that the process of fat graft resorption is typical. In patients with scalp scars, an effective method of their removal and hairline restoring is usage of the tissue expander.

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Section: Discussionmentioning

confidence: 99%

Surgical treatment of skin lesions in lupus erythematosus

Lewandowicz

Zieliński

Iljin

et al. 2014

pdia

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“…Successful fat transfer has been reported in both lupus panniculitis and DLE (Table 4). 1,40–47 Complications from the procedure are rare but can include fat necrosis requiring drainage, as seen in one case report 45 . Adequate control of the underlying inflammatory disease prior to fat transfer may help facilitate optimal results.…”

Section: Methodsmentioning

confidence: 99%

Treatments for disease damage in cutaneous lupus erythematosus: A narrative review

Joseph

Abbas

Chong

2021

Dermatologic Therapy

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Cutaneous lupus erythematosus (CLE) is an autoimmune photosensitive disorder that affects the skin. CLE lesions can have signs of skin damage including dyspigmentation, scarring, atrophy and/or alopecia. Disease damage secondary to CLE can be cosmetically disfiguring and causes patients significant distress. While many current treatments for CLE focus primarily on reducing inflammation, there are few options for managing disease damage. Providers currently lack strong guidance on managing CLE damage due to the paucity of literature on this topic. Because of this knowledge gap, we aim to provide an overview of what is currently known about the pathogenesis and management of signs of disease damage in CLE. In this narrative review, Pubmed, Ovid Medline, and Google scholar were searched for relevant articles assessing pathogenesis and treatment of disease damage. Therapeutic options for CLE damage, including hyperpigmentation (laser and camouflage), hypopigmentation (melanocyte grafting and camouflage), scarring (laser, dermabrasion, and camouflage), atrophy (filler, fat transplantation, and flap procedures), and scarring alopecia (hair transplantation and camouflage) were identified. We found that investigations of therapeutics for CLE disease damage primarily consist of case reports and small case series. Reported adverse events due to treatment for CLE disease damage range from temporary erythema and discomfort to disease reactivation and pigmentary defects. There are various treatments for disease damage for each sign of disease damage. However, more robust investigations are needed to assess disease pathogenesis and improve treatments of disease damage due to CLE.

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Lupus Erythematosus and Antiphospholipid Syndrome

Dutz,

Khosravi‐Hafshejani

2024

Rook's Textbook of Dermatology

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Lupus erythematosus is an autoimmune disease that commonly affects the skin, and may present with cutaneous only disease. This chapter reviews the forms of cutaneous lupus‐specific skin disease (discoid lupus, subacute cutaneous lupus, lupus tumidus and acute cutaneous lupus), their clinical features, pathogenesis and treatment. A review of systemic lupus erythematosus is also provided with a discussion of diagnosis, clinical features, cutaneous aspects and treatment, germane for the dermatologist. Clinical features of neonatal lupus erythematosus and the antiphospholipid antibody syndrome, more commonly seen in systemic lupus erythematosus kindreds, are also discussed.

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Autologous Fat Transfer in a Patient with Lupus Erythematosus Profundus

Cited by 4 publications

References 5 publications

Surgical treatment of skin lesions in lupus erythematosus

Surgical treatment of skin lesions in lupus erythematosus

Treatments for disease damage in cutaneous lupus erythematosus: A narrative review

Lupus Erythematosus and Antiphospholipid Syndrome

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