“…Fat grafting, commonly performed for reconstruction of soft tissue defects, is complicated by resorption rates ranging from 10% to 90% that often necessitate reoperation. [24][25][26] Initially described by Matsumoto et al in 2006, the addition of supplemental SVF cells/ASCs has been shown to improve fat graft retention. 27 However, several unknowns, including the optimum ratio of cells to lipoaspirate for the graft volume desired, remain to be determined before cell-assisted lipotransfer can be consistently used clinically.…”