Autologous fibrin glue versus sutures for conjunctival autograft in primary pterygium: a randomized clinical trial

Use of Cryopreserved Amniotic Membrane During Pterygium Excision: Health Economic Analysis

“…A total of 15 prospective comparative studies 12,15,19,[51][52][53][54][55][56][57][58][59][60][61][62] assessed the recurrence rate at six months for eyes receiving CAU with sutures or fibrin glue following excision of primary pterygium. Twelve studies were randomized controlled trials, and three studies were prospective comparative studies, in which randomization was not reported.…”

“…12,55,61 Eight studies reported the use of conjunctival limbal autograft, in which the autograft was dissected towards the cornea to include part of the superficial limbus. 12,52,[54][55][56][60][61][62] Aside from one study that reported the use of autologous fibrin glue, 51 the fibrin glue used in the studies were commercially available products such as Tisseel ® (Baxter Healthcare Corporation, Glendale, CA). No studies reported use of intra-operative MMC.…”

“…From the 15 studies, the overall recurrence rate at six months following excision of primary pterygium with CAU is 3.0% (21/691 eyes) when securing the graft with fibrin glue and 6.1% (42/694 eyes) when using sutures (Table 6). 12,15,19,[51][52][53][54][55][56][57][58][59][60][61][62] In contrast, the recurrence rate using the TissueTuck technique is 0.4% (2/486 eyes) at six months in eyes presenting with primary pterygium. 9…”