Automated assessment of heart chamber volumes and function in patients with previous myocardial infarction using multidetector computed tomography

Fuchs, Andreas; Kühl, Jørgen Tobias; Lønborg, Jacob; Engstrøm, Thomas; Vejlstrup, Niels; Køber, Lars; Kofoed, Klaus F.

doi:10.1016/j.jcct.2012.01.006

Cited by 42 publications

(22 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Automated assessment of functional CT imaging can be carried out reliably, and is in agreement with CMR determined chamber assessment [58]. In patients with a poor acoustic window and contraindications for CMR, CT can be an acceptable alternative for determining LA, LV, and LV function.…”

Section: Pre-procedural Assessmentmentioning

confidence: 55%

Arrhythmia

Bekkers¹,

Kietselaer²,

Pison³

2015

Advanced Cardiac Imaging

View full text Add to dashboard Cite

Section: Pre-procedural Assessmentmentioning

confidence: 55%

Arrhythmia

Bekkers¹,

Kietselaer²,

Pison³

2015

Advanced Cardiac Imaging

View full text Add to dashboard Cite

“…The use of two different modalities to assess cardiac volumes may introduce a bias. However, 98% of patients (121/124) were assessed with the same modality at baseline and follow-up and Fuchs et al 21 have previously shown excellent agreement between CT and CMR for LV and left atrial dimensions. In addition, fibrosis assessment was carried out using LGE 27.…”

Section: Discussionmentioning

confidence: 99%

“…A single investigator, blinded to treatment allocation, analysed images using Vitrea2 FX (Vital Images, Minnesota, USA). The chamber volumes were analysed with a semi-automated approach 21. The left atrial appendage was included, but pulmonary veins were excluded from the atrial volume.…”

Section: Methodsmentioning

confidence: 99%

Functional effects of losartan in hypertrophic cardiomyopathy—a randomised clinical trial

Axelsson¹,

Iversen²,

Vejlstrup³

et al. 2015

Heart

Self Cite

View full text Add to dashboard Cite

show abstract

“…Left ventricle volume (LVV) and LVM were analysed as previously described 15. LV myocardial perfusion (LVP) at rest was estimated by the LV myocardial attenuation density ratio (MyoAD ratio) and the transmural perfusion ratio as previously described 16…”

Section: Methodsmentioning

confidence: 99%

Nocturnal antihypertensive treatment in patients with type 1 diabetes with autonomic neuropathy and non-dipping: a randomised, placebo-controlled, double-blind cross-over trial

et al. 2016

Self Cite

View full text Add to dashboard Cite

ObjectivesCardiovascular autonomic neuropathy (CAN) and abnormal circadian blood pressure (BP) rhythm are independent cardiovascular risk factors in patients with diabetes and associations between CAN, non-dipping of nocturnal BP and coronary artery disease have been demonstrated. We aimed to test if bedtime dosing (BD) versus morning dosing (MD) of the ACE inhibitor enalapril would affect the 24-hour BP profile in patients with type 1 diabetes (T1D), CAN and non-dipping.SettingSecondary healthcare unit in Copenhagen, Denmark.Participants24 normoalbuminuric patients with T1D with CAN and non-dipping were included, consisting of mixed gender and Caucasian origin. Mean±SD age, glycosylated haemoglobin and diabetes duration were 60±7 years, 7.9±0.7% (62±7 mmol/mol) and 36±11 years.InterventionsIn this randomised, placebo-controlled, double-blind cross-over study, the patients were treated for 12 weeks with either MD (20 mg enalapril in the morning and placebo at bedtime) or BD (placebo in the morning and 20 mg enalapril at bedtime), followed by 12 weeks of switched treatment regimen.Primary and secondary outcome measuresPrimary outcome was altered dipping of nocturnal BP. Secondary outcomes included a measurable effect on other cardiovascular risk factors than BP, including left ventricular function (LVF).ResultsSystolic BP dipping increased 2.4% (0.03–4.9%; p=0.048) with BD compared to MD of enalapril. There was no increase in mean arterial pressure dipping (2.2% (−0.1% to 4.5%; p=0.07)). No difference was found on measures of LVF (p≥0.15). No adverse events were registered during the study.ConclusionsWe demonstrated that patients with T1D with CAN and non-dipping can be treated with an ACE inhibitor at night as BD as opposed to MD increased BP dipping, thereby diminishing the abnormal BP profile. The potentially beneficial effect on long-term cardiovascular risk remains to be determined.Trial registration numberEudraCT2012-002136-90; Post-results.

show abstract

Automated assessment of heart chamber volumes and function in patients with previous myocardial infarction using multidetector computed tomography

Cited by 42 publications

References 49 publications

Arrhythmia

Arrhythmia

Functional effects of losartan in hypertrophic cardiomyopathy—a randomised clinical trial

Nocturnal antihypertensive treatment in patients with type 1 diabetes with autonomic neuropathy and non-dipping: a randomised, placebo-controlled, double-blind cross-over trial

Contact Info

Product

Resources

About