Automated blood pressure monitoring for the assessment of antihypertensive treatment

Once vs twice daily administration of a fixed combination of captopril plus hydrochlorothiazide in essential hypertension: a double‐blind crossover study in known responders to a standard combination.

“…Numerous studies have showed that ambulatory blood pressure monitoring is a reliable method for evaluating whether medication can control blood pressure over 24 h (Weber, 1988). In our study, ambulatory blood pressure monitoring illustrated the similar antihypertensive efficacy of both once daily and twice daily regimens of fixed C + HCTZ combination during regular working activities.…”

“…There is increasing awareness that single measurements of blood pressure in the clinic may not accurately reflect blood pressure levels throughout the rest of the day (Pickering et al, 1985). Numerous studies have showed that ambulatory blood pressure monitoring is a reliable method for evaluating whether medication can control blood pressure over 24 h (Weber, 1988). In our study, ambulatory blood pressure monitoring illustrated the similar antihypertensive efficacy of both once daily and twice daily regimens of fixed C + HCTZ combination during regular working activities.…”

Comparison of quinapril and atenolol as single drugs or in combination with hydrochlorothiazide in moderate to severe hypertensives, using automated ambulatory monitoring.

“…To date, ambulatory blood pressure monitoring has been primarily a research tool and does not have an established clinical role in the diagnosis and management of hypertension. Nevertheless this technique has been shown to be more reliable than the casual measurement of blood pressure at the physician's office when evaluating the efficacy of antihypertensive drugs (O'Brien et al, 1989;Weber, 1988). By providing a substantial number of blood pressure values, this technique decreases withinsubject variation and greatly increases the power of blood pressure measurements (Coats et al, 1992).…”

“…The incidence of side effects was similar during the treatment with either quinapril (n = 11) or atenolol (n = 11). One subject experienced severe Raynaud's phenomenon during treatment with atenolol that resolved completely (Andren et al, 1982;Goldstein, 1990) Weber, 1988). By providing a substantial number of blood pressure values, this technique decreases withinsubject variation and greatly increases the power of blood pressure measurements (Coats et al, 1992 (Graettinger et al, 1989 (Lacourciere et al, 1990;Pickering et al, 1989).…”

Differential effects of antihypertensive drugs with differing pharmacological properties on the basal ambulatory blood pressure

“…Specifically, ambulatory BP monitoring is useful in identifying patients with 'white-coat', 'isolated clinic' or 'false' hypertension, to exclude the placebo response, and to assess antihypertensive effects throughout the day including hypotensive effects at night. 2 …”