1996
DOI: 10.1164/ajrccm.154.3.8810613
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Automated continuous positive airway pressure titration for obstructive sleep apnea syndrome.

Abstract: This study tested the effectiveness of the AutoSet self-titrating nasal continuous positive airway pressure (nCPAP) system in treating obstructive sleep apnea (OSA), and choosing a suitable pressure for subsequent conventional fixed-pressure nCPAP therapy. Twenty-one adult men with untreated OSA were studied with full polysomnography on each of four nights: diagnostic, manual and AutoSet nCPAP titration (in random order), and conventional fixed-pressure nCPAP at the pressure recommended by the AutoSet titratio… Show more

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Cited by 188 publications
(166 citation statements)
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“…Results on the feasibility of treatment with some auto-nCPAP devices have been published as preliminary studies and/or abstracts [5-7, 20, 21]. Some devices have been designed to detect respiratory events, flow limitation and snoring [5,20], whereas others have been designed to detect only respiratory events [21], or both respiratory events and snoring [6,7].…”
Section: Discussionmentioning
confidence: 99%
“…Results on the feasibility of treatment with some auto-nCPAP devices have been published as preliminary studies and/or abstracts [5-7, 20, 21]. Some devices have been designed to detect respiratory events, flow limitation and snoring [5,20], whereas others have been designed to detect only respiratory events [21], or both respiratory events and snoring [6,7].…”
Section: Discussionmentioning
confidence: 99%
“…An alternative is to automate the titration process and determine a single pressure suitable for subsequent at-home fixed pressure treatment. The validity of such a strategy in correcting sleep breathing disorders has been demonstrated when compared with manual titration [8,9]. However, whether this permits a substantial reduction in or abolition of laboratory-based tests needed to titrate CPAP in OSA patients remains unknown.…”
Section: P Lévy J-l Pepinmentioning
confidence: 99%
“…Variability in hypopnoea detection has already been mentioned and is probably critical during an "on-line" procedure such as manual titration. Arousal detection is an even more complex issue as both the criteria used [13] and the normal values [14] inspiratory flow limitation may be recognized from flow contour but this is undoubtedly more easily and accurately done automatically by a specific algorithm than by visual inspection [8,12]. On the other hand, the titration should not be performed only by increasing the pressure.…”
Section: P Lévy J-l Pepinmentioning
confidence: 99%
“…Most patients in the studies had already had a formal sleep study and some had a conventional CPAP titration or were being treated with CPAP before they were first treated with APAP. The results in such patients may differ from those of naïve, untreated patients (11). The performance of APAP under routine conditions, in home use and in a general population of patients with moderate-to-severe OSA is still unclear.…”
Section: Discussionmentioning
confidence: 97%