Automated detection of local artery wall thickness based on M-line signal processing

Hoeks, Arnold P.G.; Willekes, Christine; Boutouyrie, Pierre; Brands, Peter J.; Willigers, Jean M.; Reneman, Robert S.

doi:10.1016/s0301-5629(97)00119-1

Cited by 164 publications

(130 citation statements)

References 13 publications

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“…Second, we used a novel method to determine carotid IMT based on a single point measurement technique. 25 However, this method has shown an excellent correlation with B-mode measurements 42 ; both are strongly related to age and blood pressure, 43 which was also the case in the present study (data not shown). Additionally, we minimized measurement variation related to IMT variability along the artery by clearly defining where the measurements were taken.…”

Section: Discussioncontrasting

confidence: 42%

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Arterial Stiffness Increases With Deteriorating Glucose Tolerance Status

Henry

Kostense²,

Spijkerman³

et al. 2003

Circulation

434

385

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Background-Type 2 diabetes (DM-2) and impaired glucose metabolism (IGM) are associated with an increased cardiovascular disease risk. In nondiabetic individuals, increased arterial stiffness is an important cause of cardiovascular disease. Associations between DM-2 and IGM and arterial stiffness have not been systematically investigated. Methods and Results-In a population-based cohort (nϭ747; 278 with normal glucose metabolism, 168 with IGM, and 301 with DM-2; mean age, 68.5 years), arterial stiffness was ultrasonically estimated by distensibility and compliance of the carotid, femoral, and brachial arteries and by the carotid elastic modulus. After adjustment for age, sex, and mean arterial pressure, DM-2 was associated with increased carotid, femoral, and brachial stiffness, whereas IGM was associated only with increased femoral and brachial stiffness. .63) for femoral compliance. The brachial artery followed a pattern similar to that of the femoral artery. Increases in stiffness indices were explained by decreases in distension, increases in pulse pressure, an increase in carotid intima-media thickness, and, for the femoral artery, a decrease in diameter. Hyperglycemia or hyperinsulinemia explained only 30% of the arterial changes associated with glucose tolerance. Adjustment for conventional cardiovascular risk factors did not affect these findings. Conclusions-IGM and DM-2 are associated with increased arterial stiffness. An important part of the increased stiffness occurs before the onset of DM-2 and is explained neither by conventional cardiovascular risk factors nor by hyperglycemia or hyperinsulinemia.

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Section: Discussioncontrasting

confidence: 42%

“…This setup enables measurements of diameter, distension, and intima-media thickness (IMT). 25,26 Briefly, after a 15-minute supine rest, the artery was visualized in B-mode. An M-line was then placed at the measurement site.…”

Section: Diameter Distension and Intima-media Thicknessmentioning

confidence: 99%

Arterial Stiffness Increases With Deteriorating Glucose Tolerance Status

Henry

Kostense²,

Spijkerman³

et al. 2003

Circulation

434

385

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“…This was not due to the different characteristics of the 2 systems because they have been tested against each other and both demonstrated a very high precision of measurements, 2.2-to 6.7-fold higher than classic bidimensional echo systems. 14,15 Particularly in vEDS, the reduction in IMT was not observed at the site of the radial artery. In control subjects, carotid IMT was positively and significantly correlated with radial IMT (Figure 2), whereas most vEDS patients had carotid IMT values close to 0.4 mm despite a normal range of radial IMT values.…”

Section: Methodological Features and Study Limitationsmentioning

confidence: 97%

“…12,13 BP was monitored with an oscillometric method (Dinamap model 845, Critikon). Measurements of the right common carotid artery and radial artery parameters were obtained with high-precision echotracking devices (Wall Track System, PIE Medical, 14 and NIUS 02, SMH, 15 respectively), coupled with applanation tonometry as previously described, validated, and used in clinical studies. 12,13 A senior technician (B.L.)…”

Section: Arterial Parametersmentioning

confidence: 99%

Increased Carotid Wall Stress in Vascular Ehlers-Danlos Syndrome

et al. 2004

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Background-Vascular Ehlers-Danlos syndrome (vEDS), also known as EDS type IV, an inherited disorder of connective tissue, results from mutations in the gene encoding type III procollagen (COL3A1). Affected patients are at risk for arterial dissection or rupture, the main cause of death. To understand the pathogenesis of the vascular lesions, we used a biomechanical approach and determined steady and pulsatile wall stress. Methods and Results-Sixteen patients with vEDS and 16 age-, gender-, and blood pressure-matched control subjects were included in this cross-sectional noninvasive study. Circumferential wall stress was determined under steady and pulsatile conditions at the site of an elastic (common carotid) and a muscular (radial) artery from the measurements of intima-media thickness and internal diameter with high-resolution echo-tracking systems and either mean blood pressure or pulse pressure, respectively. At the site of the carotid artery, steady circumferential wall stress was 43% higher in vEDS patients than in control subjects (68.9Ϯ14.3 versus 48.2Ϯ12.1 kPa, PϽ0.001), and pulsatile circumferential wall stress was 22% higher (28.2Ϯ7.7 versus 23.1Ϯ5.7 kPa, PϽ0.001). Carotid intima-media thickness was 32% lower (408Ϯ56 versus 598Ϯ171 m, PϽ0.001) in vEDS patients, and internal diameter was not different between groups. Radial artery parameters were not significantly different between groups. Conclusions-In vEDS patients, an abnormally low intima-media thickness generates a higher wall stress than in control subjects at the site of an elastic artery, which may increase the risk of arterial dissection and rupture.

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“…During 4 to 6 cardiac cycles, the CCA medial diameter (MD), considered as the outer diameter, and the intima-media thickness (IMT) were recorded using a high spatial resolution ultrasound echotracking system (Wall Track System, Pie Medical) (Hoeks et al, 1997;Boutouyrie et al, 1999) over a line perpendicular to the longitudinal and transversal axes of the artery, selected on the 2D B-mode image. In addition, the CCA intraluminal pressure was also measured non-invasively with a pencil-type probe that incorporated a high-fidelity Millar strain-gauge transducer coupled with tonometry by applanation (Boutouyrie et al, 1999).…”

Section: Arterial Measurementsmentioning

confidence: 99%

Stochastic approach to estimate the arterial pressure

Eddhahak-Ouni

Masson

Allaire

et al. 2009

European Journal of Mechanics - A/Solids

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This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPTThe aim of this paper is to illustrate the application of a stochastic approach to estimate the human common carotid arterial pressure. The analysis took into account the possible random uncertainties of the problem inputs such as geometric information and mechanical model parameters so that it is called a probabilistic parametric approach. Based on the only available information reported in literature, entropy maximum principle was used to develop probabilistic density functions for every random variable. In addition, in vivo human experimental data were considered for the determination of the so-called mean or deterministic model. Furthermore, numerical simulations of Monte Carlo were carried out involving the dispersion of all the uncertain parameters. Results showed that uncertainty of 5% led to error up to 20% in the arterial pressure estimation. Convergence was proved and a region with a confidence probability of 95% was constructed to allow the prediction of the random response of the arterial pressure. Eventually, we managed numerous calculations to analyze the influence of each random variable of the problem inputs over the arterial pressure evolution.

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Automated detection of local artery wall thickness based on M-line signal processing

Cited by 164 publications

References 13 publications

Arterial Stiffness Increases With Deteriorating Glucose Tolerance Status

Arterial Stiffness Increases With Deteriorating Glucose Tolerance Status

Increased Carotid Wall Stress in Vascular Ehlers-Danlos Syndrome

Stochastic approach to estimate the arterial pressure

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