“…There are a variety of methods for extracting lung volume from a pulmonary CT scan. In order to segment lung, approaches such as global thresholding [5,6], optimal thresholding [7,8], three-dimensional (3-D)-adaptive fuzzy thresholding [9], rule-based region growing [10], connected component labeling [11], graph-cut algorithm [12], and hybrid segmentation [13] have generally been used. After initial segmentation, lung volume has been extracted using several methods, and the extracted lung volume needed to be refined to include juxta-pleural nodules.…”