Automated determination of serum cystine aminopeptidase

Watson, D.; Gibbard, S.

doi:10.1016/s0009-9120(73)80011-6

Cited by 7 publications

(2 citation statements)

References 3 publications

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“…A commercial CAP assay kit (CAP Color Test; Sankyo, Japan), based on the modified Watson method (Watson & Gibbard 1973), was used for CAP quantitation. For the determination of HSAP, the serum sample was preincubated at 65°C for 5 min prior to assay with a commercial available kit of reagents (Eiken Chemicals, Japan).…”

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confidence: 99%

Successful pregnancy in an acromegalic patient during 2-Br-α-ergocryptine (CB-154) therapy

Miyakawa

Taniyama

Koike

et al. 1982

Acta Endocrinologica

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Foeto-placental function and hormone levels in the maternal, foetal and amniotic compartments have been investigated in an acromegalic woman who was treated with 20 mg bromocriptine/day throughout gestation. Bromocriptine therapy during pregnancy had no effect on urinary oestriol excretion and plasma levels of unconjugated oestriol, progesterone, human placental lactogen, cystine aminopeptidase and heat-stable alkaline phosphatase. The maternal and foetal (cord) blood and amniotic fluid showed prolactin levels of 3.8, 6.5 and 1700 ng/ml, respectively, in the 39th week of pregnancy during bromocriptine therapy. Compared with data from normal pregnancies, these values demonstrated that bromocriptine or an active metabolite crossed the term placenta to suppress prolactin secretion from the foetal pituitary gland and that the prolactin level in amniotic fluid was scarcely affected by the drug. Maternal, foetal and amniotic fluid growth hormone levels were 27.0, 33.0 and 3.8 ng/ml, respectively, thus indicating that dopamine agonists suppress growth hormone only in acromegalic patients, and not in normal babies. Bromocriptine had no effect on thyroidstimulating hormone concentrations in the maternal, foetal and amniotic compartments.

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confidence: 99%

Successful pregnancy in an acromegalic patient during 2-Br-α-ergocryptine (CB-154) therapy

Miyakawa

Taniyama

Koike

et al. 1982

Acta Endocrinologica

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“…Preliminary experiments had shown the results obtained to be comparable though slightly lower than those found using reagents from the Radiochemical Centre, Amersham. Serum cystine aminopeptidase activity was measured by a modification of the method of Tovey (1969) and recently reported in summary (Watson and Gibbard, 1973). Kinetic measurement of the enzyme is made using Pye Unicam automation equipment AC 60/61 SP 1800 and recorder AR 25.…”

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confidence: 99%

A comparative study of five laboratory tests for foeto-placental dysfunction in late pregnancy

et al. 1973

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SYNOPSIS Five foeto-placental function tests were studied in parallel in normal and abnormal late pregnancies with a view to establishing which test or tests is most satisfactorily able to identify the mother whose foetus is in danger.A critical examination of the levels in blood serum of two enzymes, placental phosphatase isoenzyme and cystine aminopeptidase, the polypeptide hormone placental lactogen (chorionic somatomammotrophin), -and the oestrogen oestriol-17, is described.A correlation was attempted beween clinical data and the results of the above laboratory analyses and also with the daily urine oestrogen output. The plasma and urine oestriol levels proved generally to be the more useful warning tests in late pregnancy, whilst the plasma cystine aminopeptidase was the least sensitive indicator of foeto-placental dysfunction.

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A new colorimetric method for the determination of serum enzyme, γ-glutamyl transpeptidase, cystine aminopeptidase, and leucine aminopeptidase

Minato

1979

Clinica Chimica Acta

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Automated determination of serum cystine aminopeptidase

Cited by 7 publications

References 3 publications

Successful pregnancy in an acromegalic patient during 2-Br-α-ergocryptine (CB-154) therapy

Successful pregnancy in an acromegalic patient during 2-Br-α-ergocryptine (CB-154) therapy

A comparative study of five laboratory tests for foeto-placental dysfunction in late pregnancy

A new colorimetric method for the determination of serum enzyme, γ-glutamyl transpeptidase, cystine aminopeptidase, and leucine aminopeptidase

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