Institute of Toxicology, E. Merck, Darmstadt, 41nstitute of Toxicology, Boehringer, Ingelheim Kayser, K., Oberholzer, M., WeiDe, G., WeiDe, I. & v. Eberstein, H. Long distance image transfer: First results of its use in histopathological diagnosis. APMIS 99: 808-814, 1991. Histopathological images were transferred by use of normal telephone lines between three pathology institutes located in three different cities in the FRG. Images were digitized using a colour TV camera and stored in a special computerized image transmission system. The stored image was transferred and visualized on a (receiver) colour TV screen after dialing the telephone number connected to the receiver image transmission system. An additional telephone dialogue was activated by use of a normal acoustic telephone, and the diagnostic difficulties of the underlying image were discussed. Diagnostic assistance was possible in all transferred cases as well as histopathological diagnosis. Resolution of the images was set at 512x512 pixelx8 bit. Image transfer time was 3.2 min on average. The differences between the original and transferred image were measured by "retransfer" of the original image and by subtracting the two images from each other. No major transfer errors could be measured.