“… 3 The toxicity of HMs (As( v ), Cd( ii ), Cr( vi ), Pb( ii )) has become a global issue because of their presence in the food chain, as human beings are the top consumers in the food chain. 4 HMs in drinking water can cause chronic effects, including nausea, vomiting, diarrhea, kidney failure, cognitive impairment, thyroid abnormalities, muscle weakness, and cancer. 5 Chronic exposure to Cd( ii ), Cr( vi ), Ni( ii ), and Pb( ii ) in humans may cause kidney and bone damage, adverse respiratory effects, contact allergies, and neurotoxicity, respectively.…”