Automated Tube Voltage Adaptation in Combination with Advanced Modeled Iterative Reconstruction in Thoracoabdominal Third-Generation 192-Slice Dual-Source Computed Tomography

Scholtz, Jan-Erik; Wichmann, Julian L.; Hüsers, Kristina; Beeres, Martin; Nour-Eldin, Nour-Eldin A.; Frellesen, Claudia; Vogl, Thomas J.; Lehnert, Thomas

doi:10.1016/j.acra.2015.05.010

Cited by 24 publications

(25 citation statements)

References 31 publications

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“…Subanalysis of the 91 patients who underwent a WBCT-examination on the 3rd-DSCT generation and SSCT. Previous authors have put an emphasis on attenuation based automated kV-reduction, showing a dose reduction without diminution of image quality [24]. Those observations are supported by our results, where the automated attenuation based kV selection in both DSCT-systems significantly reduced the radiation output, when compared to the SSCT without automated attenuation based kV selection.…”

Section: Tablesupporting

confidence: 91%

“…In the present work we obtained similar dose reduction values, which can mostly be attributed to the newly introduced tin filter, as the tube voltage and tube current were similar if not identical. However, we applied the automated tube voltage selection in both DSCT-generations, whereas the data acquired on the 2nd-generation DSCT in the mentioned study were performed with a fixed tube voltage [24]. Our results additionally lend credence to the observation made by Leschka et al, showing a higher dose efficiency and enhanced energy separation when using the tin filter [25].…”

Section: Tablesupporting

confidence: 79%

“…Those observations are supported by our results, where the automated attenuation based kV selection in both DSCT-systems significantly reduced the radiation output, when compared to the SSCT without automated attenuation based kV selection. Using an automated dose tracking software, Scholtz et al achieved a dose reduction of 34.9% by lowering the voltage acquisition from 120 kV in the 2nd-generation DSCT to 100 kV in the 3rd-generation DSCT, while maintaining excellent image quality and soft tissue in both modality generations [24]. In the present work we obtained similar dose reduction values, which can mostly be attributed to the newly introduced tin filter, as the tube voltage and tube current were similar if not identical.…”

Section: Tablementioning

confidence: 99%

See 2 more Smart Citations

The evolution of radiation dose over time: Measurement of a patient cohort undergoing whole-body examinations on three computer tomography generations

Marcus

Koerner

Aydin

et al. 2017

European Journal of Radiology

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Section: Tablesupporting

confidence: 91%

Section: Tablesupporting

confidence: 79%

Section: Tablementioning

confidence: 99%

See 1 more Smart Citation

The evolution of radiation dose over time: Measurement of a patient cohort undergoing whole-body examinations on three computer tomography generations

Marcus

Koerner

Aydin

et al. 2017

European Journal of Radiology

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“…This study found that quantitative airway and parenchymal measurements were comparable for low‐ and ultralow‐dose protocols with the use of IR (ADMIRE). Work has previously been done validating noise levels and volume quality across doses with the incorporation of TCM and/or reconstruction methods . Our work incorporated these techniques and focused on quantitative parenchymal and airway measurements with differences measured between each protocol and the control protocol, in a biologically relevant large animal model.…”

Section: Discussionmentioning

confidence: 99%

“…Work has previously been done validating noise levels and volume quality across doses with the incorporation of TCM and/or reconstruction methods. [33][34][35][36][37] Our work incorporated these techniques and focused on quantitative parenchymal and airway measurements with differences measured between each protocol and the control protocol, in a biologically relevant large animal model. Overall, diameter measurements, wall thickness, and TABLE IV.…”

Section: Discussionmentioning

confidence: 99%

Comparison of low‐ and ultralow‐dose computed tomography protocols for quantitative lung and airway assessment

et al. 2017

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Purpose Quantitative computed tomography (CT) measures are increasingly being developed and used to characterize lung disease. With recent advances in CT technologies, we sought to evaluate the quantitative accuracy of lung imaging at low and ultra-low radiation doses with the use of iterative reconstruction (IR), tube current modulation (TCM), and spectral shaping. Methods We investigated the effect of five independent CT protocols reconstructed with IR on quantitative airway measures and global lung measures using an in-vivo large animal model as a human subject surrogate. A control protocol was chosen (NIH-SPIROMICS + TCM) and five independent protocols investigating TCM, low and ultra-low radiation dose, and spectral shaping. For all scans quantitative global parenchymal measurements (mean, median and standard deviation of the parenchymal HU, along with measures of emphysema) and global airway measurements (number of segmented airways and pi10) were generated. In addition, selected individual airway measurements (minor and major inner diameter, wall thickness, inner and outer area, inner and outer perimeter, wall area fraction, and inner equivalent circle diameter) were evaluated. Comparisons were made between control and target protocols using difference and repeatability measures. Results Estimated CT volume dose index (CTDIvol) across all protocols ranged from 7.32 mGy to 0.32 mGy. Low and ultra-low dose protocols required more manual editing and resolved fewer airway branches; yet, comparable pi10 whole lung measures were observed across all protocols. Similar trends in acquired parenchymal and airway measurements were observed across all protocols, with increased measurement differences using the ultra-low dose protocols. However, for small airways (1.9 ± 0.2mm) and medium airways (5.7 ± 0.4mm) the measurement differences across all protocols were comparable to the control protocol repeatability across breath-holds. Diameters, wall thickness, wall area fraction, and equivalent diameter had smaller measurement differences, than area and perimeter measurements. Conclusions In conclusion, the use of IR with low and ultra-low dose CT protocols with CT volume dose indices down to 0.32 mGy maintains selected quantitative parenchymal and airway measurements relevant to pulmonary disease characterization.

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Two-Phase Contrast Injection Protocol for Pediatric Cardiac Computed Tomography in Children with Congenital Heart Disease

et al. 2017

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To assess a two-phase contrast injection protocol for contrast enhancement during cardiac computed tomography (CT) in children with congenital heart disease. Forty-three children (20 boys, 23 girls) of median age 13 months (range 3 days-8.3 years) and weighing ≤ 20 kg who underwent cardiac CT using a two-phase contrast injection protocol at our institution were retrospectively identified. High-pitch spiral third-generation dual-source cardiac CT (tube voltage 70 kV) was performed with a fixed delay of 60 s after contrast injection in the order of 10 mgI/kg/s (30 s), 15 mgI/kg/s (20 s), and a saline chaser (10 s). Attenuation in the inferior vena cava (IVC), superior vena cava (SVC), right atrium (RA), right ventricle (RV), pulmonary artery (PA), left atrium (LA), left ventricle (LV), and descending aorta (AO) was compared using the Steel-Dwass and Fisher's exact tests. The median (interquartile range) attenuation in the IVC, SVC, RA, RV, PA, LA, LV, and AO was 285 (264-347) Hounsfield units (HU), 416 (370-445) HU, 368 (320-388) HU, 373 (322-417) HU, 397 (330-432) HU, 425 (373-469) HU, 435 (385-468) HU, and 437 (392-491) HU, respectively (p < 0.05, IVC vs. the other anatomic sites). There was no significant difference in diagnostic success rate for attenuation > 250 HU between the IVC (41 children, 95.3%) and the other sites (43 children, 100%). A two-phase contrast injection protocol is useful for effective contrast enhancement in pediatric cardiac CT.

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Automated Tube Voltage Adaptation in Combination with Advanced Modeled Iterative Reconstruction in Thoracoabdominal Third-Generation 192-Slice Dual-Source Computed Tomography

Cited by 24 publications

References 31 publications

The evolution of radiation dose over time: Measurement of a patient cohort undergoing whole-body examinations on three computer tomography generations

The evolution of radiation dose over time: Measurement of a patient cohort undergoing whole-body examinations on three computer tomography generations

Comparison of low‐ and ultralow‐dose computed tomography protocols for quantitative lung and airway assessment

Two-Phase Contrast Injection Protocol for Pediatric Cardiac Computed Tomography in Children with Congenital Heart Disease

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