Automatic bolus tracking in monophasic spiral CT of the liver: liver-to-lesion conspicuity

Mehnert, F.; Pereira, Philippe L.; Trübenbach, J.; Kopp, Andreas F.; Claussen, Claus D.

doi:10.1007/s003300000637

Cited by 25 publications

(21 citation statements)

References 23 publications

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“…Anatomy appears less delineated show that injection protocols with more than just one injection phase are advantageous compared to protocols that use a single injection phase. Bolus tracking is recommended for the upper abdomen [15], but not in patients with multiple trauma because of the circulatory instability present in most cases [2,6]. Instead, a fixed time delay using an amount of 150 mL seems to be the method of choice [2,6].…”

Section: Discussionmentioning

confidence: 99%

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Whole-body computed tomography for multiple traumas using a triphasic injection protocol

et al. 2008

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To evaluate a triphasic injection protocol for whole-body multidetector computed tomography (MDCT) in patients with multiple trauma. Fifty consecutive patients (41 men) were examined. Contrast medium (300 mg/mL iodine) was injected starting with 70 mL at 3 mL/s, followed by 0.1 mL/s for 8 s, and by another bolus of 75 mL at 4 mL/s. CT data acquisition started 50 s after the beginning of the first injection. Two experienced, blinded readers independently measured the density in all major arteries, veins, and parenchymatous organs. Image quality was assessed using a five-point ordinal rating scale and compared to standard injection protocols [n = 25 each for late arterial chest, portovenous abdomen, and MDCT angiography (CTA)]. With the exception of the infrarenal inferior caval vein, all blood vessels were depicted with diagnostic image quality using the multiple-trauma protocol. Arterial luminal density was slightly but significantly smaller compared to CTA (P< 0.01). Veins and parenchymatous organs were opacified significantly better compared to all other protocols (P < 0.01). Arm artifacts reduced the density of spleen and liver parenchyma significantly (P < 0.01). Similarly high image quality is achieved for arteries using the multiple-trauma protocol compared to CTA, and parenchymatous organs are depicted with better image quality compared to specialized protocols. Arm artifacts should be avoided.

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Section: Discussionmentioning

confidence: 99%

“…If the arm cannot be positioned above the head, e.g., in cases of shoulder injury [15][16][17], artifacts are inevitable. In particular, the bones of the shoulders, arms, and hands cause reduction in the luminal opacification with a spiral aspect.…”

Section: Vessel Enhancementmentioning

confidence: 99%

Whole-body computed tomography for multiple traumas using a triphasic injection protocol

et al. 2008

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“…At our institution, like many others in Japan, two types of contrast materials with an iodine concentration of 300 or 370 mg/ml are available. The purpose of this study was to investigate the effect of different iodine concentrations on aortic, portal and hepatic enhancement under the conditions of the same injection rate and time at MDCT using an automatic bolus tracking technique [16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Comparison of two contrast materials with different iodine concentrations in enhancing the density of the the aorta, portal vein and liver at multi-detector row CT: a randomized study

et al. 2004

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This work investigates differences in contrast enhancement of the aorta, portal vein and liver by two different concentrations of contrast materials using an automatic bolus tracking technique. Seventy patients were assigned randomly into one of two groups. Contrast materials with iodine concentrations of 300 and 370 mg/ml were administered to patients in groups A and B, respectively. The total iodine load (600 mg/kg) and injection time (30 s) were identical. Differences in the increase of the Hounsfield unit of the aorta, portal vein and liver between the two groups were examined by t-test. There were no significant differences between the two groups in any of the contrast enhancements of the aorta, portal vein and liver parenchyma at all phases, except for enhancement of the portal vein at the late arterial phase. Females showed better contrast enhancement of the aorta and portal vein than males. With the same iodine dose and injection time, the concentration of contrast materials did not seem to influence the efficacy of contrast enhancement of the aorta, portal vein and liver, except for the portal vein at the late arterial phase. Planning of protocols for contrast media injection may be made irrespective of the iodine concentrations.

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“…Moreover, bolus-tracking technique can be easily applied which allows a better synchronisation of the CTA scan with contrast material passage [4,7,8,9,10,11,12].…”

Section: Introductionmentioning

confidence: 99%

Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser

et al. 2003

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The aim of this study was to investigate the usefulness of saline chaser in 16-row multislice CT (16-MSCT) coronary angiography. Forty-two patients were divided into two groups for contrast material (CM) administration: group 1 (140 ml at 4 ml/s) and group 2 (100 ml at 4 ml/s followed by 40 ml of saline chaser at 4 ml/s). All patients underwent retrospectively ECG-gated 16-MSCT coronary angiography. The attenuation at the origin coronary vessels was assessed. Three regions of interest (ROIs) were drawn throughout the data set: (a) ascending aorta (ROI 1); (b) descending aorta (ROI 2); and (c) pulmonary artery (ROI 3). The attenuation in the superior vena cava was recorded (ROI 4). The average attenuation and the slope were calculated in each ROI and differences were assessed with a Student's t test. The average attenuation in the coronary vessels was not significantly different in the two groups. The average attenuations in ROI 1 were 325 and 327 HU, in ROI 2 were 328 and 329 HU and in ROI 3 were 357 and 320 HU, for groups 1 and 2, respectively (p>0.05). The slopes in ROI 1 were -0.2 and 1.1, in ROI 2 were 2.8 and 2.1 (p>0.05) and in ROI 3 were 3.9 and -9.0 (p<0.05), for groups 1 and 2, respectively. The average attenuations in ROI 4 were 927 and 643 HU (p<0.05), for groups 1 and 2, respectively. One hundred milliliters of CM with 40 ml of saline chaser provides the same attenuation as 140 ml of CM (35% less) with decreased hyper-attenuation in the superior vena cava.

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Automatic bolus tracking in monophasic spiral CT of the liver: liver-to-lesion conspicuity

Cited by 25 publications

References 23 publications

Whole-body computed tomography for multiple traumas using a triphasic injection protocol

Whole-body computed tomography for multiple traumas using a triphasic injection protocol

Comparison of two contrast materials with different iodine concentrations in enhancing the density of the the aorta, portal vein and liver at multi-detector row CT: a randomized study

Non-invasive 16-row multislice CT coronary angiography: usefulness of saline chaser

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