Automatic measurement of epidermal thickness from optical coherence tomography images using a new algorithm

Abstract

The new image processing method for measuring ET from OCT images significantly reduces calculation time for this parameter, and avoids user intervention. The main advantages of this are that data can be analyzed more rapidly and reproducibly in clinical trials.

Superficial wounding model for epidermal barrier repair studies: Comparison of erbium:YAG laser and the suction blister method

“…Measurements were performed on Day 0 before wound induction and just after wound induction, and at each evaluation visit for the two methods. Epidermal thickness and structure of the Er:YAG laser‐ and SB‐wounded areas was also evaluated by epidermal imaging using optical coherence tomography (OCT, Skindex, Isis Optronics GmbH, Mannheim, Germany) on Day 0 before and after wound induction and at each evaluation visit (D1–D4 for Group 1 and D3–D7 for Group 2). A detailed description of this method has previously been published 17.…”

Noninvasive Determination of Epidermal and Stratum Corneum Thickness in vivo Using Two-Photon Microscopy and Optical Coherence Tomography: Impact of Body Area, Age, and Gender

“…Nevertheless, the boundary between the stratum papillare and the stratum reticulare is problematic and primarily the cause for inaccuracy [9, 10]. Relatively constant references for the ET are given in the literature [14, 32].…”

Automated Assessment of Epidermal Thickness and Vascular Density of Port Wine Stains Oct Image

“…In recent years, several automated methods have been reported to assess the ET by OCT, such as A-scan analysis, 3 shapelet analysis, 11 Markov chain 12 and active contour. 13 However, it is still unknown, about the e®ectiveness of these algorithms when applied to clinical OCT images with artifacts or skin/hair debris. In this paper, we propose and demonstrate an algorithm based on energy map that can assess the mean ET correctly and e®ec-tively even under the above condition.…”