1995
DOI: 10.1111/j.1651-2227.1995.tb13638.x
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Automatic needle insertion diminishes pain during growth hormone injection

Abstract: Non-compliance in children receiving growth hormone (GH) treatment is often caused by pain on injection and difficulties in administration of GH. It has been suggested that automatic needle insertion diminishes pain perception. We quantitatively measured pain intensity on injection with two prototype pens for GH administration, providing either manual or automatic sc needle insertion, using a combined visual analogue/facial scale and a five-item scale in 18 children. With the automatic pen there was a signific… Show more

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Cited by 34 publications
(18 citation statements)
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“…169 Use of distraction techniques discussed previously, ice, and less painful injection techniques can also be efficacious. [170][171][172][173] The use of lidocaine as the diluent for ceftriaxone can decrease the pain of intramuscular injection. 174 Does the Appropriate Use of Analgesics Make Evaluation More Difficult?…”
Section: Controlling Pain Related To Needle Sticks and Other Minor Prmentioning
confidence: 99%
“…169 Use of distraction techniques discussed previously, ice, and less painful injection techniques can also be efficacious. [170][171][172][173] The use of lidocaine as the diluent for ceftriaxone can decrease the pain of intramuscular injection. 174 Does the Appropriate Use of Analgesics Make Evaluation More Difficult?…”
Section: Controlling Pain Related To Needle Sticks and Other Minor Prmentioning
confidence: 99%
“…To help reduce the sensory aspects of pain produced by needles, many pediatric hospitals have taken initiatives to ensure that children receive fewer injections, such as through the use of a central line. There have been numerous publications evaluating alternative, less painful methods of injection, such as the use of automatic needle insertion (Main, Jorgensen, Hertel, Jensen, & Jakobsen, 1995), microfabricated micro-needles (Kaushik et al, 2001), and needless injectors (Cooper, Bromley, Baranowski, & Barker, 2000). Compared to standard needle injections, needless Pediatric Procedural Pain 20 injectors have resulted in superior ratings for convenience, nervousness, pain, and overall performance (e.g., Murray et al, 2000).…”
Section: Medical Approaches Pharmacological Interventions For Pediatmentioning
confidence: 99%
“…However, injection pain is also recognized to be affected by preservatives and buffers used in GH products, factors that are product specific [15,16]. Lack of injection pain has been identified as a desirable injection device feature [17] and may directly influence adherence [18,19]. Storage-flexible products were associated with greater respondent-reported adherence, with 76% of respondents who used a storage-flexible product reporting never missing an injection per month versus 57% of those who used a refrigerationonly product.…”
Section: Discussionmentioning
confidence: 95%