Automatic regulation of the endotracheal tube cuff pressure with a portable elastomeric device. A randomised controlled study

Endotracheal Tube Overinflation Leading to Hypoxic Cardiac Arrest: A Case Report and Review of the Literature

“…A recent randomized control trial found that automated vs. manual correction of cuff pressure was associated with a significantly lower rate of underinflation (2% vs. 15%, P<0.001). However, there were no significant differences in overinflation rates (2% for both, P=0.78) [14]. In their editorial highlighting the importance of monitoring ETT intracuff pressure in ICU and anesthesia patients, Kumar et al recommend continuous intracuff pressure monitoring [15].…”

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update

“…Automated control of endotracheal-tube cuff pressure was associated with lower VAP rates in 2 small trials but this signal has not been borne out in other trials. [170][171][172][173][174] Indeed, 2 large, multicenter, randomized trials of automated cuff-pressure regulation versus thrice-daily manual cuff-pressure assessments found no difference between arms in VAP, VAE, antibiotic utilization, duration of mechanical ventilation, ICU length of stay, or mortality. 174,175 6.…”

Is It a Real Obesity Paradox?

“…For example, the definitions of weight categories by the World Health Organization may be suitable (underweight, #18.4; normal weight, 18.5-24.9; overweight, 25.0-29.9; and obesity, #30.0). 3 Our second preoccupation concerns the external validity of the results. Based on the nature of the post hoc analysis of a randomized controlled trial, the enrolled patients in this study are highly selected.…”

“…In addition, the incidence of VAP has clearly decreased in France, and the VAP rate reported by our study is in line with that reported in the large French continuous surveillance database REARAISIN (11.7%). 3 As acknowledged in the discussion of study limitations, only patients requiring mechanical ventilation for >48 hours and receiving vasopressor support for shock were included. Therefore, our results could not be generalized to patients with no vasopressor support.…”