“…Different approaches have been described to detect the luminal and external elastic membrane borders from 2-D IVUS images, including texture-based methods (Papadogiorgaki et al, 2007), knowledge-based graph searching (Bovenkamp et al, 2009), region growing (Sanz-Requena et al, 2007), radial gradient searching (Luo et al, 2003), and active contours (Sanz-Requena et al, 2007;Takagi et al, 2000). These 2-D border-detection techniques are now used online in newer IVUS imaging consoles, allowing the quantitative evaluation of lumen and plaque measurements.…”