Joint Transmission (JT) is the dynamic coordination of transmission and/or reception at multiple geographically separated sites to improve end-user service quality. When user equipment receives signals from multiple sites, downstream performance improves. An optimization problem arises in selecting the best user subset for JT within a multiple-input–multiple-output (MIMO) system. Unfortunately, a pure brute-force approach is not feasible due to exponential time growth with user combinations, unsuitable for real-time selection in mobile networks with users continuously changing in time. This article proposes quantum-compliant heuristics using quadratic unconstrained binary optimization (QUBO) for JT user scheduling. QUBO handles initial user selection, followed by brute-force exploration for the solution. Numerical results indicate that quantum-compliant methods decrease solution time without substantial accuracy loss compared to brute-force methods.