If n ≥ 3, then moduli space M 0,[n+1] , of isomorphisms classes of (n+1)-marked spheres, is a complex orbifold of dimension n − 2. Its branch locus B 0,[n+1] consists of the isomorphism classes of those (n + 1)-marked spheres with non-trivial group of conformal automorphisms. We prove that B 0,[n+1] is connected if either n ≥ 4 is even or if n ≥ 6 is divisible by 3, and that it has exactly two connected components otherwise. The orbifold M 0,[n+1] also admits a natural real structure, this being induced by the complex conjugation on the Riemann sphere. The locus M 0,[n+1] (R) of its fixed points, the real points, consists of the isomorphism classes of those marked spheres admitting an anticonformal automorphism. Inside this locus is the real locus M R 0,[n+1] , consisting of those classes of marked spheres admitting an anticonformal involution. We prove that M R 0,[n+1] is connected for n ≥ 5 odd, and that it is disconnected for n = 2r with r ≥ 5 is odd.2010 Mathematics Subject Classification. 30F10, 30F60, 32G15.