Autonomic Dysfunction P-AD001. Gastroparesis as autonomic manifestation of myasthenia gravis: A rare case report

Auliya, Putri

doi:10.1016/j.clinph.2021.02.216

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“…This can affect the tone of the vagus nerve, causing a pathophysiologic phenomenon similar to gastroparesis. Autonomic sequelae are seen with high autoantibody burden and are associated with poor outcomes as well as increased incidence of myasthenic crisis [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Predominant Intractable Nausea in the Diagnosis of Bulbar Myasthenia Gravis: A Case Study and Review of Literature

Nagar¹,

Ramakrishna²,

Khanna³

et al. 2022

Cureus

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Gastrointestinal (GI)-predominant myasthenia gravis (MG) is rare and presents a complex clinical scenario. We report the case of a 73-year-old female with dysphagia and intractable nausea found to have bulbar MG. Her symptoms persisted despite conventional MG management with plasma exchange therapy and anticholinergics. We review existing literature and discuss the clinical manifestations, diagnosis, and treatment of bulbar MG. This case highlights the need for novel MG treatment modalities in patients like ours with anomalous, GI-predominant MG who might not respond to conventional management.

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Section: Discussionmentioning

confidence: 99%