Autonomic nervous system activity during infusion of L‐arginine in patients with liver cirrhosis

Saijyo, Tetsuya; Nomura, Masahiro; Nakaya, Yutaka; Saito, Ken; Ito, Susumu

doi:10.1111/j.1600-0676.1998.tb00123.x

Cited by 8 publications

(1 citation statement)

References 27 publications

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“…It may be noted that patients with liver cirrhosis exhibit a hyperdynamic circulatory state, as indicated by tachycardia, and an increase in cardiac output accompanied by an elevated sympathetic tone [122]. Thus, patients with cirrhosis may have increased sympathetic activity and reduced vagal tone, which may account for the increased inflammatory status that is exacerbated by enhanced plasma levels of pro-inflammatory PGE2.…”

Section: Pge2 In Liver Cirrhosismentioning

confidence: 99%

Beneficial role of bioactive lipids in the pathobiology, prevention, and management of HBV, HCV and alcoholic hepatitis, NAFLD, and liver cirrhosis: A review

Das¹

2019

Journal of Advanced Research

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Section: Pge2 In Liver Cirrhosismentioning

confidence: 99%

Beneficial role of bioactive lipids in the pathobiology, prevention, and management of HBV, HCV and alcoholic hepatitis, NAFLD, and liver cirrhosis: A review

Das¹

2019

Journal of Advanced Research

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Role of nitric oxide in the regulation of cardiovascular autonomic control

1999

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Alteration in function of the cardiac autonomic nervous system has proved to be a powerful predictor of cardiac death or serious arrhythmia in patients with cardiac disease, yet little is known about the mechanisms by which this system is regulated. Recent evidence suggests that the gaseous molecule nitric oxide (NO) may act as an important mediator in this pathway. Histochemical staining techniques have identified neuronal populations that contain NO synthase within medullary cardio-regulatory sites and their peripheral autonomic pathways. Drugs that modulate the NO pathway (administered both systemically and into the central nervous system) cause changes in pre- and post-ganglionic sympathetic nerve activity that imply that NO serves to inhibit central sympathetic outflow. There is also evidence that NO may attenuate cardiovascular end-organ responses to sympathetic stimulation. Studies suggest that NO modulates cardiac vagal control, increasing the activity of central vagal motoneurons and, more contentiously, contributing to the bradycardic effects of vagal stimulation. NO also modulates so-called 'indirect' vagal inhibition of sympathetic cardiac responses. Additionally, central attenuation of baroreflex-mediated vagal control has been described. There is relatively little information available on the importance of NO in the regulation of human cardiovascular autonomic control. Further well-controlled studies are required.

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Cardiovascular Dysfunction in Cirrhosis: Pathophysiological Evidence of a Cirrhotic Cardiomyopathy

Möller

Henriksen²

2001

Scandinavian Journal of Gastroenterology

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Autonomic nervous system activity during infusion of L‐arginine in patients with liver cirrhosis

Abstract: Liver ISSN 0106-9543

Cited by 8 publications

References 27 publications

Beneficial role of bioactive lipids in the pathobiology, prevention, and management of HBV, HCV and alcoholic hepatitis, NAFLD, and liver cirrhosis: A review

Beneficial role of bioactive lipids in the pathobiology, prevention, and management of HBV, HCV and alcoholic hepatitis, NAFLD, and liver cirrhosis: A review

Role of nitric oxide in the regulation of cardiovascular autonomic control

Cardiovascular Dysfunction in Cirrhosis: Pathophysiological Evidence of a Cirrhotic Cardiomyopathy

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