Autonomic Reflex Dysfunction Is Associated With Post-Induction Hypotension in Both Diabetic and Non-Diabetic Patients

Latson, Terry W.; Ashmore, T. H.; Reinhart, Douglas J.; Klein, Kevin; Giesecke, A. H.

doi:10.1097/00000542-199209001-00103

Cited by 2 publications

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“…A diagnosis of DAN can be made based on the presence of either three [10] or one [13,14] abnormal tests for haemodynamic autonomic function. Eleven of the 16 patients had one or more abnormal tests [13,14]. The gastric emptying parameters of these 11 patients were similar to those of the remaining five DAN negative volunteers ( Table 1).…”

Section: Resultsmentioning

confidence: 99%

“…Eleven of the 16 patients had one or more abnormal tests of haemodynamic autonomic function. Although a single abnormal test has been used to diagnose haemodynamic autonomic neuropathy [13,14], 15% of healthy volunteers will also have an abnormal response to one of the five tests [22]. Only one of the 16 patients studied had three or more abnormal tests.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of standard haemodynamic tests of autonomic function and HbA1c as predictors of delayed gastric emptying in patients with type 1 diabetes mellitus

et al. 2000

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We examined the relation between chronic glycaemic control (using glycosylated haemoglobin), haemodynamic autonomic function and rate of gastric emptying in 16 patients with type 1 diabetes mellitus. Gastric emptying was measured using a paracetamol absorption technique. Parameters of gastric emptying include area under the plasma paracetamol concentration time curve. Patients were classified as diabetic autonomic neuropathy positive or negative using five standardized haemodynamic reflex tests. Area under the plasma paracetamol concentration time curve in the neuropathy positive (10.36 (4.5) mmol.-1. min) and negative (9.84 (3.0) mmol.-1. min) groups were similar (.P.=0.42) using unpaired Student's.t. -tests. Glycosylated haemoglobin concentration and area under the plasma paracetamol concentration time curve (.n.=16) demonstrated a Pearson's correlation co-efficient of 0.24. Neither tests of haemodynamic autonomic function, nor concentration of glycosylated haemoglobin, are predictive of diabetic gastroparesis.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%