Biomimetic and biohybrid micro/nanoâstructures involve the replication and creation of technologies, structures, and materials based on biological systems at the micrometer and nanometer scale. These strategies harness the natural biological principles to develop innovative treatment methods and advanced microstructure devices for noninvasive therapies. In this study, a detailed overview of fabrication processes, magnetically assisted locomotive techniques, and potential applications of biomimetic and biohybrid micro/nanoâmachines are presented. The latest advancements in magnetically actuated biomimetic structures, such as annelidâwormâlike microswimmers, jellyfishâshaped microparticles, fishâshaped microswimmers, and walnutâshaped micromotors are explored. Additionally, the magnetic biohybrid systems, including sunflower seedâbased microâperforators, nanomotors extracted from the bamboo stem, sperm cellâbased micromotors, bacteriaâbased robots, scaffoldâbased microrobots, DNAâbased micromotors, microalgaeâbased microswimmers, and red blood cellâbased microswimmers are also examined. A thorough investigation of the magnetically assisted locomotive behavior of these microstructure devices in biological Newtonian fluids, featuring corkâscrew motion, undulatory motion, surface wrinkling motion, traveling waveâlike motion, and ciliary stroke motion is discussed. Furthermore, unprecedented and innovative treatment methods developed using these minuscule devices such as cervical cancer treatment using tetrapod hybrid sperm micromotors, tissue regeneration using silk fibroin proteinâbased magnetic microscale scaffolds, and doxorubicin drug delivery using mushroomâbased microrobots is extensively presented.