Autoregulation of cerebral blood flow in severe diffuse axonal brain injury: the role of neuroanatomical factors

Abstract

The obtained data may indicate the presence of central (neurogenic) pathways of cerebral vessel tone regulation; traumatic injury of the pathways leads to a more severe and prolonged period of impaired ACBF. Probably, injury to these regulatory structures in some patients has an indirect effect on the course of intracranial hypertension. Further experimental and clinical studies in this direction are needed to elucidate all elements of neurogenic regulation of cerebral vessel tone and ACBF mechanisms.

Advances in biomarkers for vasospasm – Towards a future blood-based diagnostic test

“…Furthermore, other pathologies and conditions have begun to be correlated with non-traditional biomarkers that may be helpful for vasospasm diagnosis, such as certain bacteria flora in mycotic aneurysms and genetic markers in traumatic brain injury. 95 , 96 , 97 Obtaining different biodata from patients to enter into a hypothetical vasospasm-diagnostic model may require additional samples or data to be collected from patients, which may complicate adoption of a hybrid test.…”

Study of Brain Circadian Rhythms in Patients with Chronic Disorders of Consciousness and Healthy Individuals Using Microwave Radiometry

“…The main way to remove excess heat is the convection path, provided with a powerful influx of arterial blood (about 20% of the minute blood volume (MBV)). Due to the mechanisms of autoregulation, cerebral blood flow is relatively independent of the general hemodynamic within the known limits of changes in systemic arterial pressure [ 20 ]. This relative independence of the regulation of blood circulation in the brain regions and general cerebral perfusion can affect the processes of heat elimination and creates the basis for the relative independence of variations in cerebral and basal temperature.…”