Autosomal Recessive Total Congenital Anonychia, in a Saudi family

Abstract

The autosomal recessive total congenital anonychia is a rare genetic disorder. In this manuscript we are reporting the occurrence of this trait in a Saudi Arabian family.

Simple congenital anonychia in an Iranian family

“…In literature review there were rare case reports of total or near total simple anonychia with AR inheritance pattern especially in Iran, Saudi Arabia, Turkey, India and Kazakhstan probably due to consanguineous marriages [1][2][3][4]6,[8][9][10][11]. We reported this case because of rare presentation but we guess it is not an extremely rare disorder and probably some of these cases have been unreported as it has been shown in our patient pedigree.…”

Anonychia congenita in different generations of a single Saudi family

“… 3 , 6 , 10 - 13 In KSA, it has been reported in a single patient and in 2 members of the same generation in another family. 10 , 14 The 3 patients in this study had complete anonychia as an isolated and asymptomatic condition which marks them as one of the rare reported cases in Saudi Arabia, as its running in different generations of a single family.…”

“…9 Nevertheless, there are few other reported cases in Turkey, Russia, Great Britain, United States of America, Holland, Brazil, Iran, India, Kazakhstan, Lebanon, Kuwait, Finland, and in Germany. 3,6,[10][11][12][13] In KSA, it has been reported in a single patient and in 2 members of the same generation in another family. 10,14 The 3 patients in this study had complete anonychia as an isolated and asymptomatic condition which marks them as one of the rare reported cases in Saudi Arabia, as its running in different generations of a single family.…”