A new era in modern dentistry has emerged where tooth loss is no longer an issue as a result of rapid advancements in implantation and alveolar ridge reconstruction. Despite its wide range of indications, autotransplantation is dependent upon careful patient selection and a suitable technique to ensure successful results both functionally and aesthetically. It is possible to restore physiological occlusion, aesthetics, and masticatory function by varying implant length, diameter, surface, and design, along with autogenous, alogenous, alloplastic, or xenogenous bone substitutes. However, none of the technologies that are used in implant dentistry today can adapt to a child's growing jaw during adolescence. Thus, the young age of the patient restricts implants and creates a challenge for dentists wishing to replace missing teeth. Therefore, tooth autotransplantation can be a good option for treatment. Our objective in this review is to highlight the biological principles required for the successful autotransplantation of teeth. Limits, indications, and prognoses will be analyzed. Hopefully, with increased awareness and acceptance in the dental profession, autotransplantation will become another viable treatment option for those with compromised teeth who still have significant growth potential.