Availability of a Zinc Amino Acid Chelate for Growing Pigs

Susaki, Hisashi; Matsui, Tohru; Ashida, Kouzou; Fujita, Shoji; Nakajima, Takashi; Yano, Hideo

doi:10.2508/chikusan.70.124

Cited by 8 publications

(11 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The stomacal Zn solubility was low (54% to 84% on 100 kg BW pigs) compared to measures observed by Dintzis et al (1995) even though pH was 4.5 and extraction methods for measuring soluble Zn were similar. The intestinal Zn solubility in piglets was, however, comparable with those of Dintzis et al (1995) who reported values of 21% in the jejunum when feeding 24 mg/kg Zn, Susaki et al (1999) with values of 11% in ileum when supplementing the diet with 25 mg/kg Zn, and those observed by Ashida et al (2000) also showed values of 29% in small intestine when feeding 65 mg/kg Zn.…”

Section: Discussionmentioning

confidence: 60%

“…Previous Schlegel, Nys and Jondreville research suggested that Zn availability depends on Zn solubility in the digesta (Susaki et al, 1999), whereas Zn solubility may depend on various factors including digesta pH (Cao et al, 2000;Jongbloed et al, 2002), dietary Zn concentration (Dintzis et al, 1995;Susaki et al, 1999), supplemented Zn source (Cao et al, 2000) and interactions between dietary Zn and diet composition (Ammerman et al, 1995;Jongbloed et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

“…Calcium reinforces this reduced Zn availability by stabilizing phytates (Oberleas et al, 1966). According to Dintzis et al (1995) and Susaki et al (1999), these antagonists alter Zn availability by depressing its solubility in the digestive tract. Demonstrations of increased Zn availability when feeding organic Zn sources compared to Zn sulfate in the presence of phytate were reported by Power et al (1994) and Schlegel and Windisch (2006) in rats.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Zinc availability and digestive zinc solubility in piglets and broilers fed diets varying in their phytate contents, phytase activity and supplemented zinc source

Schlegel

Nys

Jondreville

2010

Animal

View full text Add to dashboard Cite

The study was conducted to evaluate the effects of dietary zinc addition (0 or 15 mg/kg of Zn as inorganic or organic zinc) to three maize-soybean meal basal diets varying in their native Zn, phytic P contents and phytase activity (expressed in kg of feed: P2 with 25 mg Zn and 1.3 g phytic P, P1 with 38 mg Zn and 2.3 g phytic P or P1/ENZ being P1 including 500 units (FTU) of microbial phytase per kg) in two monogastric species (piglets, broilers). Measured parameters were growth performance, zinc status (plasma, and bone zinc) and soluble zinc in digesta (stomach, gizzard and intestine). The nine experimental diets were fed for 20 days either to weaned piglets (six replicates per treatment) or to 1-day-old broilers (10 replicates per treatment). Animal performance was not affected by dietary treatments ( P . 0.05) except that all P2 diets improved body weight gain and feed conversion ratio in piglets ( P , 0.05). Piglets fed P2 diets had a better Zn status than those fed P1 diets ( P , 0.05). In both species, Zn status was improved with supplemental Zn ( P , 0.05), irrespective of Zn source. Phytase supplementation improved piglet Zn status to a higher extent than adding dietary Zn, whereas in broilers, phytase was less efficient than supplemental Zn. Digestive Zn concentrations reflected the quantity of ingested Zn. Soluble Zn (mg/kg dry matter) and Zn solubility (% of total Zn content) were highest in gizzard contents, which also presented lower pH values than stomach or intestines. The intestinal Zn solubility was higher in piglet fed organic Zn than those fed inorganic Zn ( P , 0.01). Phytase increased soluble Zn in piglet stomach ( P , 0.001) and intestine ( P 5 0.1), but not in broiler gizzard and intestinal contents. These results demonstrate (i) that dietary zinc was used more efficiently by broilers than by piglets, most probably due to the lower gizzard pH and its related higher zinc solubility; (ii) that zinc supplementation, irrespective of zinc source, was successful in improving animal's zinc status; and (iii) suggest that supplemented Zn availability was independent from the diet formulation. Finally, the present data confirm that phytase was efficient in increasing digestive soluble Zn and improving zinc status in piglets. However, the magnitude of these effects was lower in broilers probably due to the naturally higher Zn availability in poultry than in swine.

show abstract

Section: Discussionmentioning

confidence: 60%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Zinc availability and digestive zinc solubility in piglets and broilers fed diets varying in their phytate contents, phytase activity and supplemented zinc source

Schlegel

Nys

Jondreville

2010

Animal

View full text Add to dashboard Cite

show abstract

“…These indicators were relevant for the estimation of the relative bioavailability value (RBV) of the sources only with Zn levels below the inflexion point [3,35]. Nevertheless, some Zn sources were previously compared with dietary Zn supply above this point [7,29,32]. All the indicators of Zn status we investigated in this study, except growth performance and bone bending moment, responded linearly to the dietary Zn level.…”

Section: Zn Balancementioning

confidence: 99%

Bioavailability of two sources of zinc in weanling pigs

Dourmad

Guinotte²,

Nys

2002

Anim. Res.

View full text Add to dashboard Cite

-Thirty-two pigs, weaned at 28 days of age with an average body weight of 9 kg, were used in an experiment devoted to the assessment of the bioavailability of an organic Zn source (ZnOrg) compared to Zn sulfate. Pigs were fed a basal diet containing 28 mg·kg -1 of Zn supplemented with ZnSO 4 or ZnOrg to provide 0, 10, 20 and 30 mg·kg -1 of supplemental Zn. In order to reduce the amount and the variability of their Zn stores, pigs were fed the basal diet for a 7-day adjustment period preceding a 19-day experimental period. Growth performance and bone bending moment were not affected by the level nor the source of zinc. On the contrary, plasma zinc concentration and alkaline phosphatase activity (P < 0.001), bone zinc concentration (P < 0.001), liver and empty body zinc concentrations (P < 0.01) as well as the amount of Zn retained estimated both by the balance technique (BT) (P < 0.001) and by the comparative slaughter technique (CST) (P < 0.01) increased linearly in response to supplemental Zn. However, the two Zn sources exhibited a similar bioavailability. Twenty-seven percent of Zn intake was retained when measured by means of the balance technique, regardless of the dietary level or zinc source. Zn retention was 54% lower when measured by means of the CST as compared to the BT. (0)2 23 48 50 80; e-mail: jondreville@st-gilles.rennes.inra.fr de croissance et le moment de flexion de l'os n'ont été affectés ni par le niveau ni par la source de zinc supplémentaire. Au contraire, la teneur en zinc et l'activité de la phosphatase alcaline du plasma (P < 0,001), les teneurs en zinc osseuse (P < 0,001), hépatique et corporelle (P < 0,01) ainsi que la quantité de zinc retenu estimée par la technique du bilan (P < 0,001) et celle des abattages comparés (P < 0,01) augmentaient linéairement avec l'addition du zinc. Cependant, aucune différence entre les sources n'a été détectée. Le coefficient de rétention de zinc, estimé par la technique du bilan, était de 27 % en moyenne, indépendamment du niveau ou de la source de zinc supplémentaire. Estimée par la technique des abattages comparés, la rétention de Zn était de 54 % inférieure à la valeur obtenue selon la technique du bilan.porc / zinc / biodisponibilité / source / indicateur

show abstract

“…The data from Analysis I suggests that broilers are more efficient in using ZN N than piglets and the data from Analysis II show that ZN N was negatively affected by PP NH in piglets and that Phytase S was more efficient in piglets to improve ZN N bioavailability than in broilers. Zinc bioavailability results from dietary Zn solubility in the digestive tract before absorption (Susaki et al, 1999), which is dependent from pH conditions (Cao et al, 2000;Jongbloed et al, 2002). Early in 1963, Lease measured that 66% of Zn from soybean meal was soluble when the raw material was previously digested with pepsin at pH 3, followed with an alcalinization to pH 6.8.…”

Section: Description Of the Databasesmentioning

confidence: 99%

Bioavailability of zinc sources and their interaction with phytates in broilers and piglets

Schlegel

Sauvant

Jondreville

2013

Animal

View full text Add to dashboard Cite

Zinc (Zn) is essential for swine and poultry and native Zn concentrations in feedstuffs are too low to meet their Zn requirement. Dietary Zn bioavailability is affected by phytate, phytase and Zn supplemented in organic form is considered as more bioavailable than inorganic sources. A meta-analysis using GLM procedures was processed using broiler and piglet databases to investigate, within the physiological response of Zn, (1) the bioavailability of inorganic and organic Zn sources (Analysis I); (2) the bioavailability of native and inorganic Zn dependent from dietary phytates, vegetal and supplemental phytase activity (Analysis II). Analysis I: the bioavailability of organic Zn relative to inorganic Zn sources ranged, depending on the variable, from 85 to 117 never different from 100 ( P . 0.05). The coefficients of determination of the regressions were 0.91 in broilers and above 0.89 in piglets. Analysis II: in broilers, bone Zn was explained by supplemental Zn (linear and quadratic, P , 0.001) and by supplemental phytase (linear, P , 0.001). In piglets, the interaction between dietary Zn and phytates/phytases was investigated by means of a new variable combining dietary phytic phosphorus (PP) and phytase activity. This new variable represents the remaining dietary PP after its hydrolysis in the digestive tract, mainly due to phytase and is called non-hydrolyzed phytic phosphorus (PP NH ). Bone Zn was increased with native Zn ( P , 0.001), but to a lower extent in high PP or low phytase diets (ZN N 3 PP NH , P , 0.001). In contrast, the increase in bone zinc in response to supplemental Zn ( P , 0.001) was not modulated by PP NH ( P . 0.05). The coefficients of determination of the regressions were 0.92 in broilers and above 0.92 in piglets. The results from the two meta-analyses suggest that (1) broilers and piglets use supplemented Zn, independent from Zn source; (2) broiler use native Zn and the use is slightly enhanced with supplemental phytase; (3) however, piglets are limited in the use of native Zn because of the antagonism of non-hydrolyzed dietary phytate. This explains the higher efficacy of phytase in improving Zn availability in this specie.

show abstract

Availability of a Zinc Amino Acid Chelate for Growing Pigs

Cited by 8 publications

References 19 publications

Zinc availability and digestive zinc solubility in piglets and broilers fed diets varying in their phytate contents, phytase activity and supplemented zinc source

Zinc availability and digestive zinc solubility in piglets and broilers fed diets varying in their phytate contents, phytase activity and supplemented zinc source

Bioavailability of two sources of zinc in weanling pigs

Bioavailability of zinc sources and their interaction with phytates in broilers and piglets

Contact Info

Product

Resources

About