Availability of antidotes in 70 hospitals in Catalonia

Broto-Sumalla, Antoni; Rabanal, Manel; García-Pelaéz, Milagros; Aguilar-Salmerón, Raquel; Gamarra-Martínez, Edurne Fernández de; Martínez-Sánchez, Lídia; Gaspar-Caro, María-José; Nogué-Xarau, Santiago

doi:10.1016/j.medcle.2017.11.024

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Antidotes are available for a limited number of substances causing intoxication, and timely administration of an appropriate antidote improves the clinical picture. However, many centers have problems with their supplies of antidotes [15]. In a study by Andiran et al [7], an antidote was administered to 7.9% of patients who presented with poisoning.…”

Section: Discussionmentioning

confidence: 99%

Retrospective evaluation of poisonings in a pediatric intensive care unit: 4 years of experience

Ergül¹,

Torun²

2018

Ann Clin Anal Med

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Aim: We defined clinical characteristics of patients admitted to the pediatric intensive care unit (PICU) with a diagnosis of poisoning. Material and Method: The study was designed as a retrospective, uni-center, cross-sectional study. All patients who were admitted to the PICU for poisoning by a chemical substance between December 2012 and June 2017 were included in the study. We recorded the frequency of patients admitted to the PICU with poisoning as well as their clinical characteristics. Results: Overall, 1093 patients were admitted to PICU during study period including 223 patients with poisoning due to chemical substances. The incidence of admissions due to poisoning was 11.7%. The poisoning was unintentional in 58.3% (n = 130) of patients, and it was associated with suicidal intent in 39.9% (n = 89) and substance abuse in 1.8% (n = 4). Neither clinical nor laboratory findings were observed in 69.5% (n = 155) of these patients. An antidote was used in 17.5% of patients, with N-acetyl cysteine being the antidote most commonly used. A combination of an analgesicantitussive-decongestant was the most common agent (7.7%) resulting in poisoning. Colchicine intoxication was seen in 3.4% of patients, a markedly higher incidence than reported in the literature. Discussion: It is important to identify characteristics in poisoning as a basis for taking appropriate measures and developing treatment plans.

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Section: Discussionmentioning

confidence: 99%

Retrospective evaluation of poisonings in a pediatric intensive care unit: 4 years of experience

Ergül¹,

Torun²

2018

Ann Clin Anal Med

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“…In Catalonia, Spain, a similar study was carried out in 70 hospitals, in 2015. The global availability of antidotes ranged between 42.1%–100% for tertiary hospitals, and between 23%–100% in regional hospitals,6 depending on the antidote. The study revealed how difficult it is for hospitals to maintain an appropriate stock of some high-cost antidotes.…”

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confidence: 99%