Availability of laboratory diagnosis of gonorrhoea and its meaning in case reporting in Shandong province, China

Chen, Xinlong; Gan, Yanling; Liu, Dianchang

doi:10.21203/rs.3.rs-35168/v1

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…Male-to-male transmission is the main transmission route of HIV in Shandong, accounting for 69.3% of new infections in 2020. 22 …”

Section: Methodsmentioning

confidence: 99%

Effectiveness of instant versus text messaging intervention on antiretroviral therapy adherence among men who have sex with men living with HIV

Jiao,

Ma,

Lin

et al. 2024

DIGITAL HEALTH

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Objective This study aimed to compare the effectiveness of instant versus text messaging intervention (TMI) on antiretroviral therapy (ART) adherence among men who have sex with men (MSM) living with HIV. Methods This study was conducted in an infectious disease hospital of Jinan, China from October 2020 to June 2021, using non-randomized concurrent controlled design to compare the effectiveness of instant messaging intervention (IMI) versus TMI. The intervention strategies (health messaging, medication reminder, and peer education) and contents were consistent between the two groups, and the difference was service delivery method and type of information. The primary outcome was the proportion of achieving optimal ART adherence, defined as never missing any doses and delayed any doses more than 1 hour. Results A total of 217 participants (including 72 in TMI group and 145 in IMI group) were included in the study. The proportion of achieving optimal adherence was higher in IMI group than TMI group at the first follow-up (90.2% versus 77.6%, p = 0.021) and second follow-up (86.5% versus 76.6%, p = 0.083). The effect of IMI versus TMI on improving ART adherence was found not to be statistically significant (risk ratio (RR) = 1.93, 95% confidence interval (CI): 0.95–3.94) in complete-case analysis. However, when excluding participants who did not adhere to the interventions, a significant improvement was observed (RR = 2.77, 95%CI: 1.21–6.38). More participants in IMI group expressed highly rated satisfaction to the intervention services than those in TMI group (67.3% versus 50.0%). Conclusions The IMI demonstrated superior efficacy over TMI in improving ART adherence and satisfaction with intervention services. It is suggested that future digital health interventions targeting ART adherence should prioritize instant messaging with multimedia information in areas with Internet access. Trial registration The study was registered at the Chinese Clinical Trial Register (ChiCTR), with number [ChiCTR2000041282].

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“…Male-to-male transmission is the main transmission route of HIV in Shandong, accounting for 69.3% of new infections in 2020. 22 …”

Section: Methodsmentioning

confidence: 99%

Effectiveness of instant versus text messaging intervention on antiretroviral therapy adherence among men who have sex with men living with HIV

Jiao,

Ma,

Lin

et al. 2024

DIGITAL HEALTH

View full text Add to dashboard Cite

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Availability of Laboratory Diagnosis of Gonorrhoea and Its Meaning in Case Reporting in Shandong Province, China

Chen

Gan

Liu

2023

CCID

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Background Gonorrhea, caused by the bacterium Neisseria gonorrhoeae (NG), is a major public health concern worldwide. Aim of the Study The aim of this study is to understand the availability of laboratory diagnosis of gonorrhoea in Shandong province and its meaning in case reporting. Methods Two surveys were conducted among hospitals providing clinical services for sexually transmitted infection (STI) in Shandong Province in 2012 and 2018. The availability of laboratory tests for NG and distribution of reported gonorrhea cases were compared among different hospitals provided clinical services for STI in Shandong province. Descriptive analysis and Chi-square were used for statistical analysis. Results Smear, culture and PCR tests for NG were used among 301(74.69%), 123(30.52%), 43(10.67%) hospitals in 2012 and 356(74.48%), 176(36.82%) and 73(15.27%) hospitals in 2018, respectively. Significant differences were observed in the availability of smear among hospitals at different levels (X 2 =12.159, p=0.000) and with different affiliations (X 2 =4.551, p=0.033) in 2018. Significant differences were observed in the availability of culture and PCR tests among hospitals at different levels both in 2012 (X 2 =34.532, p=0.000; X 2 =7.380, p=0.007) and 2018 (X 2 =49.820, p=0.000; X 2 =21.658, p=0.000). The availability of culture and PCR tests for NG among hospitals in 2018 was higher than that in 2012 (X 2 =3.870, p=0.049; X 2 =4.050, p=0.044). More hospitals reported gonorrhea cases in 2018 than in 2012 (X 2 =6.768, p=0.009). A significant difference was observed in distribution of case reporting among hospitals at different levels in 2018 (X 2 =6.975, p=0.008) and among different types of hospital both in 2012 (X 2 =52.362, p=0.000) and 2018 (X 2 =74.478, p=0.000). Conclusion Poor availability of NG laboratory tests affects case reporting, and which is a crucial reason leading to underreporting of gonorrhea cases in Shandong province.

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Availability of laboratory diagnosis of gonorrhoea and its meaning in case reporting in Shandong province, China

Cited by 2 publications

References 26 publications

Effectiveness of instant versus text messaging intervention on antiretroviral therapy adherence among men who have sex with men living with HIV

Effectiveness of instant versus text messaging intervention on antiretroviral therapy adherence among men who have sex with men living with HIV

Availability of Laboratory Diagnosis of Gonorrhoea and Its Meaning in Case Reporting in Shandong Province, China

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