Avaliação da anestesia epidural com lidocaína associada ao tramadol ou à dexmedetomidina, em gatas submetidas à ovariosalpingohisterectomia, anestesiadas com propofol

Sande, J.Q.; Souza, Thamires Barreto Silva; Kersul, I; Anjos, N.P.; Filho, Emanoel Ferreira Martins; Barbosa, Vivian Fernanda

doi:10.1590/1678-4162-10536

Cited by 2 publications

(3 citation statements)

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“…It blocks the transmission of nociceptive stimulus by the afferent neuronal pathways before these reach the CNS. This method is thought to be simple, affordable, and has a low incidence of complications [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

“…Lidocaine is a local anaesthetic frequently used for epidural injection in short surgical procedures and promotes reversible nerve conduction blockade [20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

“…In small animal veterinary care, the lumbosacral technique is most frequently employed to access the epidural space [20,22,28,29]. Few studies have examined the utility of lidocaine administered lumbosacrally in cats for OHE [21,23,[25][26][27].…”

Section: Introductionmentioning

confidence: 99%

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Antinociceptive Effect of a Sacro-Coccygeal Epidural of Morphine and Lidocaine in Cats Undergoing Ovariohysterectomy

Dourado

Gomes

Teixeira

et al. 2022

Veterinary Sciences

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Background: A commonly described analgesic protocol for ovariohysterectomy (OHE) combines systemic opioids, sedatives, and non-steroidal anti-inflammatory drugs. However, systemic analgesia does not fully prevent perioperative visceral and somatic pain triggered by the surgical stimulus. Objectives: To compare the analgesic effects and quality of recovery of systemic analgesia with those of a sacrococcygeal epidural injection of lidocaine and morphine in cats undergoing elective OHE. Methods: Twenty domestic female cats were premedicated with dexmedetomidine (0.01 mg kg−1 IM) and alfaxalone (1.5 mg kg−1 IM) and randomly assigned to one of two analgesic protocols: methadone (0.2 mg kg−1 IM) in the control group CTR (n = 10) and methadone (0.1 mg kg−1 IM) + epidural (lidocaine 2% (0.3 mL kg−1) + morphine 1% (0.1 mg kg−1) diluted with NaCl 0.9% to a total volume of 1.5 mL in the SCC-E group (n = 10). General anaesthesia was induced with alfaxalone (1 mg kg−1 IV) and maintained with sevoflurane in 100% oxygen. Non-invasive blood arterial pressure and cardiorespiratory variables were recorded. The quality of recovery was assessed using a simple descriptive scale. Before surgery and 1, 2, 3, 4, 6, and 8 h post-op pain was assessed using the UNESP-Botucatu multidimensional composite pain scale (MCPS) and mechanical nociception thresholds (MNT). The repeated measures analysis of variance (ANOVA) was used to compare groups over time. Comparison between groups was performed using independent samples t-test if the assumption of normality was verified, or the Mann–Whitney test. The chi-square test of independence and exact Fisher’s test were used to compare groups according to recovery quality. Results: Heart rate and systolic arterial pressure increased significantly from baseline values in the CTR group and did not change in the SCC-E group. In the CTR group, MNT and UNESP-Botucatu-MCPS scores increased significantly from baseline for all assessment points and the first 3 h, respectively, whereas this did not occur in the SCC-E group. Conclusions and clinical relevance: Based on our results, the SCC-E administration of lidocaine 2% with morphine 1% is a reasonable option to provide perioperative analgesia in cats submitted to OHE, compared to a systemic protocol alone.

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Section: Introductionmentioning

confidence: 99%

“…Lidocaine is a local anaesthetic frequently used for epidural injection in short surgical procedures and promotes reversible nerve conduction blockade [20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%