OBJECTIVE: The objective of this study was to assess global quality of life and the factors associated with it in long-lived older adults registered with family health centers. Global quality of life was measured using the two general questions on the World Health Organization Quality of Life instrument. METHODOLOGY: This was a cross-sectional, quantitative study based on secondary data from a sample of 100 older adults. RESULTS: The results of analyses revealed a mean age of 84.20 years, 77% of the sample were female, 46% had spent between 1 and 4 years in education, 63% were widowed, 76% had an income equivalent to one to two times the minimum wage, 77% had systemic arterial hypertension, 34% had diabetes mellitus, 27% had cardiovascular disease, 74% had social support, and 63% exhibited depressive symptomology. The frequency of satisfactory global quality of life in the sample studied was 35%. CONCLUSIONS: In relation to global quality of life, assessed in terms of interviewees’ satisfaction with their lives and health in conjunction, the majority of the study population reported not being satisfied. After completion of all statistical analyses, factors associated with dissatisfaction were social support, depression, and osteoarthritis.