Avaliação Da Xerostomia Em Pacientes Com Câncer De Cabeça E Pescoço Submetidos Ao Tratamento Radioterápico

Silva, Renata Glaucia Barros da; Ramos, Aline Maria Pereira Cruz; Aben-Athar, Cintia Yolette Urbano Pauxis; Palha, Ingrid Renny Silva; Pinheiro, Adriana de Sá; Soares, Tamires de Nazaré

doi:10.21527/2176-7114.2017.32.5-14

Cited by 3 publications

(5 citation statements)

References 7 publications

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“…This considerable decrease demonstrates that, although none of the analyzed patients underwent surgical excision of the salivary glands, the treatment of choice may have caused indirect injury to the salivary glands, which resulted in a reduction in SFV during the treatment period. This result is similar to that of a study by Silva et al (2017) 19 who, using the technique of spontaneous sialometry, found that reduced salivary flow before radiotherapy was present in 35% of 20 patients, and 100% of the patients had some degree of reduction in salivary flow at the end of radiotherapy. It is noteworthy that in the present study, SFV was evaluated using stimulated saliva.…”

Section: Discussionsupporting

confidence: 90%

“…In addition, they found that hyposalivation persisted for up to six weeks post--radiotherapy. Similar to the studies by Silva et al (2017) 19 and Lima et al (2004) 10 , in the present study, the daily dose of irradiation was 200 cGy, and although the final treatment dose varied, it was always > 4,000 cGy; therefore, it was capable of causing permanent damage to the salivary glands 20 .…”

Section: Discussionsupporting

confidence: 89%

“…This increase in mean VAS scores reveals that a higher VAS score associated with a reduction in the SFV results in more interference in the functional capacity and, consequently, in the patient's quality of life. Silva et al (2017), by applying the EORTC H&N35 questionnaire, showed significant differences in the domains irritation in the mouth (p = 0.0020), choking (p = 0.0005) and sticky saliva (p = 0.0313), before and after radiotherapy.…”

Section: Discussionmentioning

confidence: 96%

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Correlation between hyposalivation and xerostomia in patients with head and neck cancer

Cella¹,

Dantas²,

Fortuna³

et al. 2022

J Oral Diag

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Introduction: Saliva plays an important role in maintaining oral homeostasis. However, cancer treatment can induce transient or permanent adverse effects on the salivary glands. Objective: This study aimed to evaluate the correlation between xerostomia and salivary flow velocity (SFV) in patients undergoing antineoplastic treatment for head and neck cancer (HNC), under the Public Health System in the city of Salvador-BA. Materials and Methods: This cross-sectional observational study evaluated medical records of patients diagnosed with HNC and treated by the Oncology Service of the High Complexity Unit in Oncology Nossa Senhora de Fátima - Irmã Dulce Social Works - dental team between January 2019 and March 2020. After anamnesis, stimulated saliva was collected at the 1st and 24th radiotherapy sessions to quantify SFV, and a xerostomia questionnaire was administered for assessments based on a visual analogue scale (VAS). Descriptive statistics were performed, and categorical variables are presented as means, percentages, and coefficients of variation. Results: Medical records of 200 patients were assessed and 16 patients were included in the study. The sociodemographic profile showed a predominance of men (62.50%), aged between 46 and 70 years (56.25%), of mixed ethnicity (43.75%), with incomplete primary education (43.75%), alcoholics (56.25%), and non-smokers (56.25%). Tumor and treatment data showed a predominance of exclusive radiotherapy (50%), location in the larynx (31.25%), and T1/T2 staging (56.25%). The mean SFV of patients was 1.75 mL/min and 0.71 mL/min at the 1st and 24th session, respectively, revealing that irradiation reduced SFV. All domains of the xerostomia scale showed an increase in the means obtained, which indicated worsening of xerostomia between the 1st and 24th sessions. Conclusions: An inverse correlation was observed between the mean VAS scores and SFV in patients with HNC. Further studies to correlate hyposalivation (objective sign) with xerostomia (subjective symptoms) are recommended.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 96%

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Correlation between hyposalivation and xerostomia in patients with head and neck cancer

Cella¹,

Dantas²,

Fortuna³

et al. 2022

J Oral Diag

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“…Silva et al 25 avaliaram a relação entre a xerostomia e a qualidade de vida relacionada à saúde bucal em pacientes com câncer de cabeça. Os resultados apontaram alta prevalência no sexo feminino (85%), com idades entre 51 e 70 anos (40%), frequentemente diagnosticadas com câncer de cabeça e pescoço.…”

Section: Discussionunclassified

Avaliação da Hipossalivação e Xerostomia em Pacientes Oncológicos em Tratamento Quimioterápico

Diniz,

Oliveira,

Viana Filho

2024

Rev. Bras. Cancerol.

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Introdução: Pacientes oncológicos tratados com quimioterapia apresentam efeitos adversos. Na boca, a hipossalivação e a xerostomia são relatadas como achados frequentes oriundos desse tratamento. Objetivo: Investigar a ocorrência de xerostomia e hipossalivação em pacientes oncológicos em tratamento quimioterápico. Método: Estudo transversal quantitativo, com coleta de dados realizada no Hospital São Vicente de Paulo, em João Pessoa, Paraíba, no setor de oncologia, entre agosto de 2022 e março de 2023. Os pacientes foram submetidos a um exame clínico, seguido da análise do fluxo salivar não estimulado e do preenchimento do instrumento Inventário de Xerostomia. Os dados foram analisados por meio de estatística descritiva e inferencial com auxílio do software Jamovi (versão 1.8.4). Resultados: Participaram do estudo 78 indivíduos com média de idade de 53 anos (±12,5), predominantemente do sexo feminino (n=63; 80,8%) e com diagnóstico de tumores sólidos (n=70; 89,7%). A hipossalivação foi diagnosticada em 59% dos pacientes (n=46), enquanto a xerostomia foi relatada por todos os indivíduos (n=78; 100%), sendo categorizada como amena (n=13; 16,7%) ou moderada (n=65; 83,3%). Houve diferença entre o fluxo salivar de pacientes com tumores sólidos e hematológicos, sendo os indivíduos com tumores sólidos os que apresentaram menor fluxo salivar (p = 0,0027, teste U de Mann-Whitney). Além disso, pessoas com hipossalivação possuem um risco aumentado de desenvolver xerostomia moderada (RR = 0,349; IC = 0,127 – 0,955; p = 0,006, teste Exato de Fisher). Conclusão: Indivíduos diagnosticados com hipossalivação neste estudo possuem risco aumentado de relatar a presença da xerostomia em graus moderados durante o tratamento quimioterápico.

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“…O diagnóstico é realizado através de inspeção da mucosa oral e pela sialometria, um teste muito efetivo que busca identificar o fluxo salivar. O tratamento é paliativo e consiste na estimulação da saliva do paciente (BARBIERI; COSTA; GUERRA, 2020;SILVA et al,2017).…”

Section: Abordagem E Tratamento Das Manifestações Orais Em Decorrência Daunclassified

Principais manifestações bucais em pacientes submetidos à quimioterapia: abordagem e tratamento odontológico

Silva¹,

Queiróz²,

Silva³

2021

Revista Multidisciplinar Do Nordeste Mineiro

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realizando o controle e adequação do meio bucal, eliminando focos de infecções. Quando há o comprometimento da mucosa oral durante a fase de tratamento, o cirurgião-dentista na equipe multiprofissional entra com a terapia de tratamento adequado e eficaz para cada manifestação oral, sendo elas lesões ou sequelas, buscando minimizar os danos ocasionados pelos efeitos das drogas quimioterápicas, garantindo uma melhor qualidade de vida e a sobrevida do paciente, pois suas complicações podem agravar as condições sistêmicas dos pacientes.

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Avaliação Da Xerostomia Em Pacientes Com Câncer De Cabeça E Pescoço Submetidos Ao Tratamento Radioterápico

Cited by 3 publications

References 7 publications

Correlation between hyposalivation and xerostomia in patients with head and neck cancer

Correlation between hyposalivation and xerostomia in patients with head and neck cancer

Avaliação da Hipossalivação e Xerostomia em Pacientes Oncológicos em Tratamento Quimioterápico

Principais manifestações bucais em pacientes submetidos à quimioterapia: abordagem e tratamento odontológico

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