DOI: 10.47749/t/unicamp.2020.1161630
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Avaliação dos efeitos da terapia biológica com infliximabe na colite de exclusão

Andress Godoy Delben

Abstract: Introduction: Diversion colitis (DC) is a chronic inflammatory process that develops in the mucosa of the colonic segments devoid of fecal stream. The increase in the production of reactive oxygen species and inflammatory cytokines in these segments suggests that the DC has etiopathogenic molecular mechanisms like what occurs in IBD. While the use of anti-TNF-α antibodies, particularly infliximab, represents one of the most effective therapeutic strategies for the treatment of IBD, little is known about the ef… Show more

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