2023
DOI: 10.3390/ani13142358
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Avian Leukosis: Will We Be Able to Get Rid of It?

Sergio Fandiño,
Esperanza Gomez-Lucia,
Laura Benítez
et al.

Abstract: Avian leukosis viruses (ALVs) have been virtually eradicated from commercial poultry. However, some niches remain as pockets from which this group of viruses may reemerge and induce economic losses. Such is the case of fancy, hobby, backyard chickens and indigenous or native breeds, which are not as strictly inspected as commercial poultry and which have been found to harbor ALVs. In addition, the genome of both poultry and of several gamebird species contain endogenous retroviral sequences. Circumstances that… Show more

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Cited by 8 publications
(12 citation statements)
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“…The most common avian retrovirus that causes a variety of neoplastic diseases in chicken is the avian leukosis virus (ALV) 2 . Globally, the ALV morbidity and mortality rates contributed to the poultry industry’s economic decline 1 , 3 .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The most common avian retrovirus that causes a variety of neoplastic diseases in chicken is the avian leukosis virus (ALV) 2 . Globally, the ALV morbidity and mortality rates contributed to the poultry industry’s economic decline 1 , 3 .…”
Section: Discussionmentioning
confidence: 99%
“…Avian leukosis virus (ALV) is one of the most prevalent retroviruses causing neoplasms in chickens 1 , 2 . ALV related to the genus Alpharetrovirus and subfamily Orthoretrovirinae 3 .…”
Section: Introductionmentioning
confidence: 99%
“…Avian Leukosis Virus (ALV) is a globally distributed pathogen that mainly affects chickens, causing oncogenesis and immunosuppression in a fraction of infected individuals as well as a decrease in several productivity indicators [ 1 , 2 ]. ALV is an Alpharetrovirus ; as such, infection is permanent among individuals and easily transmitted, especially in industrial poultry settings where chickens may be crowded.…”
Section: Introductionmentioning
confidence: 99%
“…The LTR has three regions: U3 contains enhancer elements and the promoter; R is where transcription starts; and U5 contains post-translation regulatory elements [ 2 ]. LTRs and env are the major pathogenic determinants in retroviruses, including Alpharetrovirus , with relevance in the replication cycle and in tropism [ 7 , 8 , 9 ].…”
Section: Introductionmentioning
confidence: 99%
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