1986
DOI: 10.1159/000212771
|View full text |Cite
|
Sign up to set email alerts
|

Avoidance Acquisition in Adult and Senescent Rats

Abstract: Male rats aged 6, 19, or 33 months were trained successively in one- and two-way avoidance tasks. The one-way avoidance test consisted of up to 30 trials given in a single session with the conditional stimulus (CS; 14-kHz tone) presented for either 3 s or for 10 s in separate groups. Senescent rats performed poorest, middle-aged rats intermediately, and young adult rats best. Failure of the longer CS to yield better acquisition than the short CS in the senescent group suggested that the age-related deficit pro… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
3
0

Year Published

1988
1988
1994
1994

Publication Types

Select...
6

Relationship

0
6

Authors

Journals

citations
Cited by 14 publications
(3 citation statements)
references
References 7 publications
0
3
0
Order By: Relevance
“…These two last groups did not differ from each other. On the other hand, Fuchs, Martin, Bender, and Halting (1986) effect in a one-way active-avoidance task. Young rats (6 months) performed the best, old ones (33 months) the worst, and middle-aged rats (19 months) intermediately.…”
Section: Discussionmentioning
confidence: 96%
“…These two last groups did not differ from each other. On the other hand, Fuchs, Martin, Bender, and Halting (1986) effect in a one-way active-avoidance task. Young rats (6 months) performed the best, old ones (33 months) the worst, and middle-aged rats (19 months) intermediately.…”
Section: Discussionmentioning
confidence: 96%
“…Although results with the avoidance task confirmed the general prediction that behavioral deficits should develop more rapidly in the autoimmune strains when compared with normal mice, the specific involvement of learning and memory processes could not be directly inferred from the avoidance data. A decline of avoidance learning is a consistent finding in aged rodents [Freund and Walker, 1971;Fuchs et al, 1987;La1 and Forster, 1986;La1 et al, 1986;Stavnes and Sprott, 19751, but this paradigm is sensitive to factors other than learning and memory capacity which might be altered as a function of age. Therefore, in a series of follow-up analyses we attempted to rule out non-learning/memory-related factors as explanations for the acquisition data (e.g., sensorimotor or motivational deficits) [see Forster et al, 1988b,d;La1 and Forster, 19881.…”
Section: Learning and Memory Deficits In Autoimmune Genotypesmentioning
confidence: 81%
“…The one-way, step-up active avoidance paradigm employed in our laboratory [Forster et al, 1988b] has proved reliable in differentiating young and aged C57BLi6 mice in several investigations [La1 and Forster, 1986;La1 et al, 19861. Moreover, other laboratories have reported agc-rclated acquiqition deficits in normal mice and rats using similar paradigms [Freund and Walker, 1971;Fuchs et al, 1987;Stavnes and Sprott, 197.51. However, it is difficult to attribute performance deficits on this task to "memory" or "learning" abilities to the exclusion of other factors [Arenberg and Robertson-Tchabo, 1977;Kubanis and Zornetzer, 19811, as was evident in our post hoc analyses addressing this problem.…”
Section: Learning Memory and Sensorimotor Processes In Autoimmune Gmentioning
confidence: 90%