Avoiding misdiagnosis in ceruminous gland tumours

Lassaletta, Luis; Patrón, Mercedes; Olóriz, Javier Navas; Perez, Rosa; Gavilán, Javiér

doi:10.1016/s0385-8146(03)00055-5

Cited by 41 publications

(44 citation statements)

References 6 publications

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“…Tumors arising from these glands are extremely rare and resemble those arising from sweat glands elsewhere in the body [4,[11][12][13]. Wetli, et al, indicated that malignant tumors out-number benign (2.5:1) with equal male to female distribution [14].…”

Section: Discussionmentioning

confidence: 99%

“…Complete or adequate local excision is the treatment of choice; however, residual tumor often remains because of the difficulty of surgery at this location leading to recurrence [4,19,20]. However, there is no evidence of recurrence for these tumors in the literature, with a mean follow-up time of 15 years [11,12,14]. Our patient underwent total surgical excision of the mass along with the over lining skin and showed good healing process without signs of recurrence up to seven months later.…”

Section: Discussionmentioning

confidence: 99%

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Ceruminous Gland Adenoma of External Auditory Canal- A Case Report

Almuhanna¹,

Alkadi²

2016

J Oto Rec Surg

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Ceruminous Adenoma (CA) is a benign neoplasm of ceruminous glands. Developing exclusively in the external auditory canal (EAC) with benign clinical behavior and was first reported by Hang in 1894. It is rare in humans and poses a diagnostic problem for the clinician, due to the variety of clinical presentations. This tumor is mainly composed of the ceruminous gland cells (modified apocrine sweat glands). These glands are localized deep in the skin mostly in the cartilaginous part of the external auditory meatus. We are presenting a 45 year old female patient who was referred to our otology department with a two year history of right ear blockage with progressive hearing loss, her other medical history was unremarkable. The surgical finding under microscope showed soft tissue mass under the skin that fulfilled half of the posterior inferior portion of the external auditory canal (EAC) that was completely excised under general anesthesia utilizing a postaurical approach. The excised tumor specimen after proper staining confirmed the diagnosis of ceruminous adenoma. In conclusion the CA is benign rear tumor raised from ceruminous gland in EAC slowly growing when getting bigger can block the EAC leading to heating loss; it can be presented with variety of symptom such as mild otolgia, ear blockage sensation and hearing loss treatment of choice is complete excision along with over line skin to prevent recurrence.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Ceruminous Gland Adenoma of External Auditory Canal- A Case Report

Almuhanna¹,

Alkadi²

2016

J Oto Rec Surg

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“…Wetli et al [3] distinguished four categories of ceruminomas, namely the ceruminous adenoma, the pleomorphic adenoma, the ceruminous adenocarcinoma and the ceruminous adenoid cystic carcinoma. Histopathological examination findings may sometimes be inconclusive [4] in terms of cell of origin and presence of malignancy and hence use of immunohistochemistry is advocated in such situations using tissue markers like cerumen pigment, CK5, 6, 7, S-100 protein, and p63 [5]. Benign adenomas need only local excision and regular follow up where as malignant carcinomas are treated with wide local excision with adequate margin and followed by radiotherapy.…”

Section: Discussionmentioning

confidence: 99%

Adenomatous Neoplasia Presenting as Aural Polyp

Madhira

Qaiyum

Moorthy

et al. 2011

Indian J Otolaryngol Head Neck Surg

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Adenomatous neoplasia or glandular tumours in the ear are very rare to occur. We are reporting two patients who presented with polypoid mass in external auditory canal of whom one patient was diagnosed to have ceruminous adenoma of external auditory canal and the other adenomatous carcinoma of middle ear based on histopathology findings of biopsied specimen. Review of available literature shows that both ceruminous adenoma of external auditory canal and adenocarcinoma of middle are very rare to occur and are even difficult to diagnose histopathologically. We would like to emphasize the importance of considering even such rare pathologies while evaluating aural polyps.

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“…Cuando el tumor rompe el tímpano, incluso inadvertidamente para el otorrinolaringólogo, la lesión puede rotularse como del oído externo y generar confusión con el adenoma de glándulas de cerumen (16,17). Esta última lesión está compuesta por dos líneas celulares, una interna, rectangular, de características apocrinas con gránulos PAS y ZN perinucleares de pigmento pardo, y células mioepiteliales que son reactivas para S100, p63 y CK5/6, entre otros marcadores (18,19).…”

Section: Discussionunclassified

Adenoma del oído medio

Medina¹

2009

biomedica

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Las neoplasias del oído medio son lesiones raras que, generalmente, plantean retos diagnósticos por la escasa información existente sobre su biología y la carencia de uniformidad de criterios para su análisis. Se presenta el caso de un tumor de oído observado clínicamente en el canal auditivo externo, el cual protruía del oído medio a través del tímpano, y en cuyo espécimen de resección se encontró un tumor epitelial benigno con una de sus superficies revestida por epitelio escamoso. La escasa información clínica inicial incrementó la dificultad diagnóstica y para su diagnóstico se requirió apoyo en técnicas de histoquímica e inmunohistoquímica. El diagnóstico definitivo fue adenoma del oído medio. Además, se hace una revisión del tema y se plantean algunas claves diagnósticas sobre este tipo de lesiones.Palabras clave: adenoma/patología, oído medio, inmunohistoquímica, diagnóstico diferencial, tumor carcinoide. Middle ear adenomaMiddle ear neoplasms are rare lesions and difficult to diagnose due to limited information about their biology and the lack of standard criteria for their analysis. Herein, a middle ear neoplasm is described that became apparent because of its appearance in the external ear duct as it protruded from the middle ear through the eardrum. Following resection, the specimen was determined to be a benign epithelial tumor. Absence of adequate clinical information complicated the diagnosis; therefore,histochemistry and immunohistochemistry analyses were necessary to reach the final diagnosis of middle ear adenoma. Diagnostic criteria are proposed to properly diagnose these types of lesions.

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Avoiding misdiagnosis in ceruminous gland tumours

Cited by 41 publications

References 6 publications

Ceruminous Gland Adenoma of External Auditory Canal- A Case Report

Ceruminous Gland Adenoma of External Auditory Canal- A Case Report

Adenomatous Neoplasia Presenting as Aural Polyp

Adenoma del oído medio

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