Awareness about laryngopharyngeal reflux disease among Chinese otolaryngologists: a nationwide survey

Xiao, Shuifang; Li, Jinrang; Zheng, Hongliang; Li, Xiangping; Yang, Hui; Zhang, Junbo; Peng, Xiaoxia; Zhou, Shui‐Hong; Zhao, Chen; Chen, Donghui; Xiao, Xianjin; Shi, Li; Hui, Hongxiang; Tao, Zhenfeng; Chen, Xiong; Liu, Yehai; Qu, Shenhong; Wang, Guangke; Chen, Ting; Cui, Xiaobo; Tian, Linli; Zhou, Wenzhong; Fang, Hongyan; Huang, Yuyu; Yu, Guodong; Lin, Zhenqun; Tang, Liang; He, Jie; Ma, Ruixia; Yu, Zhaoyan

doi:10.1136/bmjopen-2021-058852

Cited by 2 publications

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“…As the easiest and quickest method, the symptom questionnaire is a screening tool that should not be overlooked in clinical practice. In China, it is used by most hospitals to help screening LPR 4 …”

Section: Introductionmentioning

confidence: 99%

“…In China, it is used by most hospitals to help screening LPR. 4 The Reflux Symptom Index (RSI) was first reported by Belafsky et al in 2002, and LPR can be considered when the RSI score is greater than 13. 5 Due to its simplicity and low cost, the RSI has been the most common tool used for screening LPR and patient follow-up around the world.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Reflux Symptom Score versus Reflux Symptom Index in screening laryngopharyngeal reflux

et al. 2022

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ObjectivesTo compare the screening value of the Reflux Symptom Score (RSS) and the Reflux Symptom Index (RSI) for laryngopharyngeal reflux (LPR).MethodsAll included patients attending the Department of Otolaryngology at the Sixth Medical Center of the PLA General Hospital from February 2022 to August 2022, completed the RSS and the RSI and underwent 24‐hour hypopharyngeal‐esophageal multichannel intraluminal impedance‐pH (24 h HEMII‐pH) monitoring. The results of 24 h HEMII‐pH were used as a diagnostic criterion for LPR, consistency between two questionnaires (RSS, RSI) and 24 h HEMII‐pH was compared by the weighted Cohen's kappa statistic and the screening value of RSS and RSI for LPR was compared by receiver operating characteristics analysis.ResultsA total of 77 patients, 58 males, and 19 females, were included. The Kappa values of between RSS, RSI, and 24 h HEMII‐pH were 0.663 (p < 0.001) and 0.213 (p < 0.05), respectively. The sensitivity of RSS and RSI were 92.8% and 48.2%, respectively, the specificity was 71.4% and 80.9%. The negative predictive value and positive predictive value of RSI were 36.9%, 87.1%, and that of RSS were 78.9%, 89.6%. The area under curve of the RSS (0.783; 95% CI = 0.53, 0.75) is significantly higher than RSI (0.633; 95% CI = 0.72, 0.90).ConclusionThe RSS has a higher consistency and better screening value for LPR compared to RSI. In addition, the RSS includes more reflux symptoms, which may reduce the number of missed diagnoses in patients with LPR to some extent.Level of Evidence3 Laryngoscope, 133:2104–2109, 2023

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of Reflux Symptom Score versus Reflux Symptom Index in screening laryngopharyngeal reflux

et al. 2022

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Laryngopharyngeal Reflux in Otolaryngology-Head and Neck Surgery Clinic: An Epidemiological Survey

Wang,

Liang,

Luo

et al. 2024

Ear Nose Throat J

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Background and Objectives: Laryngopharyngeal reflux disease (LPRD) has been implicated in the etiology of many laryngeal disorders and is also closely related to the occurrence and progression of a variety of throat diseases, including chronic cough, leukoplakia of the larynx, dysphonia, and even laryngeal tumors. LPRD can significantly reduce the quality of life of patients and cause substantial medical and economic burdens to the society. Reflux Symptom Index (RSI), a self-administered 9-item outcomes instrument for laryngopharyngeal reflux (LPR), has been widely used to screen for LPRD, but there is a lack of feasibility studies on the use of RSI for LPRD screening and alternative diagnostic tools in otolaryngology-head and neck surgery (OHNS) clinics. To study the incidence, clinical characteristics, diagnostic status, and influencing factors of LPRD at OHNS clinics, RSI as an alternative diagnostic tool has also been studied. LPRD was defined as RSI > 13. Methods: Systematic collection of data by the RSI questionnaire was used to identify patients in the outpatient clinic suffering from LPRD; in addition, the personal history of participants was collected. Follow-up observation was carried out for 6 months for patients with suspected LPRD (RSI > 13), including whether they were treated with standardized anti-reflux therapy, and the questionnaire based on RSI was completed again after treatment. Results: The LPRD rate was 7.92% (94/1187) in this survey. The proportions of LPRD patients with smoking history (vs no smoking) and alcohol consumption history (vs. no alcohol consumption) were significantly higher ( χ2 values: 7.025 and 4.562, and P values: .008 and .033; respectively). Smoking significantly increased the risk of LPRD (OR: 2.140, 95% CI: 1.058-4.331, P = .034). Among patients with LPRD positive, the incidence of “foreign body sensation in the throat” (symptom 8) score equal to 5 was the highest (19.15%). The severity of “excess mucus in the throat or postnasal drip” (symptom 3) contributed mostly to the total RSI score in patients with LPRD ( r = .409, P < .001). ROC curve analysis showed that RSI ≥ 14 had a sensitivity of 72.9% and a specificity of 71.4% for the diagnosis of LPRD, with AUC = 0.797 (95% CI: 0.577-0.884, P < .001). Conclusions: The incidence of LPRD was high in patients we examined in OHNS clinics. We recommend that RSI can be used by otolaryngologists as a reliable tool for screening and diagnosing LPRD in OHNS clinics, which is beneficial for clinical practice.

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Awareness about laryngopharyngeal reflux disease among Chinese otolaryngologists: a nationwide survey

Cited by 2 publications

References 36 publications

Comparison of Reflux Symptom Score versus Reflux Symptom Index in screening laryngopharyngeal reflux

Comparison of Reflux Symptom Score versus Reflux Symptom Index in screening laryngopharyngeal reflux

Laryngopharyngeal Reflux in Otolaryngology-Head and Neck Surgery Clinic: An Epidemiological Survey

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