Awareness during anaesthesia: A comparison of anaesthesia with nitrous oxide-oxygen and nitrous oxide-oxygen with Innovar®

Ninety-nine unselected patients were given a standardized general anaesthetic with fentanyl 1.5 ixg-kg -I every 30 minutes and were randomly divided into three equal groups; Group I patients received naloxone 0. l rag, Group II naloxone 0.2 mg and Group llI n',floxone 0.4 mg intravenously at the end of the operation and after the reversal of neuromuscular blockade. After naloxone the level of consciousness lightened and the response to stimulus increased: the changes were significant in all three groups and the actual changes were significantly greater in Groups II and Ill compared with Group I. In the Recovery Room there was no significant difference among the Groups for shivering, nausea, vomiting or pain. The incidence of operative awareness was one per cent and that of dreaming eight per cent and this was unrelated to naloxone dosage. Patient acceptance was high, seven patients not wanting this type of anaesthesia again due to (a) light premedication (inherent in the study design), two patients; (b) nausea and vomiting, four patients; and (c) slow awakening, one patient.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Awareness during anaesthesia: A comparison of anaesthesia with nitrous oxide-oxygen and nitrous oxide-oxygen with Innovar®

Cited by 8 publications

References 9 publications

Anaesthetic interventions for prevention of awareness during surgery

Anaesthetic interventions for prevention of awareness during surgery

A study of anaesthesia depth by power spectral analysis of the electroencephalogram (EEG)

Studies in fentanyl-supplemented anaesthesia: Awareness and effect of naloxone on early post-operative recovery

Contact Info

Product

Resources

About