Awareness of possible complications associated with direct composite restorations: A multinational survey among dentists from 13 countries with meta-analysis

Lehmann, Anna; Nijakowski, Kacper; Jankowski, Jakub; Donnermeyer, David; Palma, Paulo J.; Drobac, Milan; Martins, João Filipe Brochado; Pertek Hatipoğlu, Fatma; Tulegenova, Indira; Javed, Muhammad Qasim; Alharkan, Hamad Mohammad; Bekjanova, Olga; Wyzga, Sylvia; Alkhawas, Moataz-Bellah Ahmed Mohamed; Kudenga, Rutendo; Hatipoğlu, Ömer; Surdacka, Anna

doi:10.1016/j.jdent.2024.105009

Journal of Dentistry

2024

DOI: 10.1016/j.jdent.2024.105009

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Awareness of possible complications associated with direct composite restorations: A multinational survey among dentists from 13 countries with meta-analysis

Anna Lehmann,

Kacper Nijakowski,

Jakub Jankowski

et al.

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Cited by 3 publications

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Proteomic Analysis of Fibroblasts Exposed to Resin Composite Release

Flottes,

Dursun

2024

Proteomics Clinical Apps

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ObjectiveTo investigate the potential effects of products released by a resin composite on the proteome of human gingival fibroblasts.MethodsFifteen resin composite cylinders of a Bis‐GMA‐based resin composite (Tetric EvoCeram, Ivoclar) were made and placed in a culture medium for 24 h. Then, 30 mL of this medium was placed for 72 h in contact with human gingival fibroblasts and a second control group consisted of cells placed in culture medium only. Afterward, cells were collected, washed, and their proteins extracted. Three two‐dimensional electrophoresis were performed per condition. Image analysis of the gels was carried out to highlight the differential protein spots. These spots were then analyzed by an ESI/qTOF mass spectrometer. Finally, specific databases provided protein identification, their interactions, and the pathways where they are implicated.ResultsDelta2D software allowed the detection of 21 spots of different proteins. The MASCOT identified 28 proteins. Five proteins from four spots were upregulated, 23 proteins from 17 spots were downregulated. The UniProt database showed that all these proteins were involved in cellular architecture, structural modifications and quality control of proteins, cellular homeostasis, and metabolic pathways. The STRING database revealed the interactions between the regulated proteins. The GO enrichment analysis showed that 19 pathways were affected.SignificanceThe products released from the resin composite tested led to changes in the fibroblast proteome. Under the conditions of this study, resin composite released products can cause early adverse effects on cells, but without complete inhibition of their cellular functions.

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Proteomic Analysis of Fibroblasts Exposed to Resin Composite Release

Flottes,

Dursun

2024

Proteomics Clinical Apps

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Clinical Difficulties Related to Direct Composite Restorations: A Multinational Survey

Lehmann,

Nijakowski,

Jankowski

et al. 2024

International Dental Journal

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Influence of Exposure Distance on Light Irradiance of Dental Curing Lamps in Various Operating Modes

Lehmann,

Nijakowski,

Mroczyk

et al. 2024

Applied Sciences

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The efficiency of photopolymerisation significantly impacts achieving a high degree of conversion and, consequently, determines the success and strength of resin-based composite (RBC) restorations. The study aimed to measure the light irradiance of selected LED curing lamps, taking into account various exposure modes and the increased distance of the light source from the radiometer surface. The study material consisted of 21 LED polymerisation lamps of a single type (Woodpecker Medical Instrument Co., Guilin, China) with three exposure modes: standard, soft start, and pulse. During the measurement, the distance was increased from 0 mm to 8 mm, every 2 mm. Light irradiance measurements were made with a Bluephase Meter II photometer (Ivoclar Vivadent, Opfikon, Switzerland). Increasing the distance affected the soft mode the most, causing a significant drop in light irradiance on the photometer. Standard mode coped best with distance. Even at a distance of 0 mm, the soft start mode does not reach the power of the standard and pulse modes. The standard mode seems to be the most clinically effective, especially if it is planned to polymerise a material in a deep cavity. The soft start mode, as the least resistant to increasing distance, is recommended for use in front teeth or the cervical area.

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Awareness of possible complications associated with direct composite restorations: A multinational survey among dentists from 13 countries with meta-analysis

Cited by 3 publications

References 40 publications

Proteomic Analysis of Fibroblasts Exposed to Resin Composite Release

Proteomic Analysis of Fibroblasts Exposed to Resin Composite Release

Clinical Difficulties Related to Direct Composite Restorations: A Multinational Survey

Influence of Exposure Distance on Light Irradiance of Dental Curing Lamps in Various Operating Modes

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