Awareness of the COVID-19 Outbreak and Resultant Depressive Tendencies in Patients with Severe Alzheimer’s Disease

Tsugawa, Akito; Sakurai, Shu; Inagawa, Yuta; Hirose, Daisuke; Kaneko, Yoshitsugu; Ogawa, Yoshihide; Serisawa, Shuntaro; Takahashi, Naoto; Sakurai, Hirofumi; Kanetaka, Hidekazu; Hirao, Kentaro; Shimizu, Soichiro

doi:10.3233/jad-200832

Cited by 17 publications

(20 citation statements)

References 6 publications

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“…Another theme, related to the prevention of COVID‐19 in dementia, was the reduced ability of many people living with dementia to understand and comply with pandemic restrictions, social distancing and the use of face masks, 50–53 potentially increasing vulnerability to COVID‐19 infection. Long‐term care facility characteristics, such as size, degree of crowding, low levels of testing and personal protective equipment (PPE) were related to more COVID‐19 outbreaks 58–60 .…”

Section: Resultsmentioning

confidence: 99%

Dementia wellbeing and COVID‐19: Review and expert consensus on current research and knowledge gaps

Liu

Howard

Banerjee

et al. 2021

Int J Geriat Psychiatry

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Objectives In response to a commissioned research update on dementia during the COVID‐19 pandemic, a UK‐based working group, comprising dementia researchers from a range of fields and disciplines, aimed to describe the impact of the pandemic on dementia wellbeing and identify priorities for future research. Methods We supplemented a rapid literature search (including unpublished, non‐peer reviewed and ongoing studies/reports) on dementia wellbeing in the context of COVID‐19 with expert group members' consensus about future research needs. From this we generated potential research questions the group judged to be relevant that were not covered by the existing literature. Results Themes emerged from 141 studies within the six domains of the NHS England COVID‐19 Dementia Wellbeing Pathway: Preventing Well, Diagnosing Well, Treating Well, Supporting Well, Living Well and Dying Well. We describe current research findings and knowledge gaps relating to the impact on people affected by dementia (individuals with a diagnosis, their carers and social contacts, health and social care practitioners and volunteers), services, research activities and organisations. Broad themes included the potential benefits and risks of new models of working including remote healthcare, the need for population‐representative longitudinal studies to monitor longer‐term impacts, and the importance of reporting dementia‐related findings within broader health and care studies. Conclusions The COVID‐19 pandemic has had a disproportionately negative impact on people affected by dementia. Researchers and funding organisations have responded rapidly to try to understand the impacts. Future research should highlight and resolve outstanding questions to develop evidence‐based measures to improve the quality of life of people affected by dementia.

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Section: Resultsmentioning

confidence: 99%

Dementia wellbeing and COVID‐19: Review and expert consensus on current research and knowledge gaps

Liu

Howard

Banerjee

et al. 2021

Int J Geriat Psychiatry

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“…According to a psychiatric study, patients with moderate to severe dementia have no understanding of COVID-19 protection measures and have to be persuaded to wear masks constantly [80].…”

Section: Psychiatric Side Effects and Dangersmentioning

confidence: 99%

Is a Mask That Covers the Mouth and Nose Free from Undesirable Side Effects in Everyday Use and Free of Potential Hazards?

Kisielinski

Giboni

Prescher³

et al. 2021

IJERPH

140

172

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Many countries introduced the requirement to wear masks in public spaces for containing SARS-CoV-2 making it commonplace in 2020. Up until now, there has been no comprehensive investigation as to the adverse health effects masks can cause. The aim was to find, test, evaluate and compile scientifically proven related side effects of wearing masks. For a quantitative evaluation, 44 mostly experimental studies were referenced, and for a substantive evaluation, 65 publications were found. The literature revealed relevant adverse effects of masks in numerous disciplines. In this paper, we refer to the psychological and physical deterioration as well as multiple symptoms described because of their consistent, recurrent and uniform presentation from different disciplines as a Mask-Induced Exhaustion Syndrome (MIES). We objectified evaluation evidenced changes in respiratory physiology of mask wearers with significant correlation of O2 drop and fatigue (p < 0.05), a clustered co-occurrence of respiratory impairment and O2 drop (67%), N95 mask and CO2 rise (82%), N95 mask and O2 drop (72%), N95 mask and headache (60%), respiratory impairment and temperature rise (88%), but also temperature rise and moisture (100%) under the masks. Extended mask-wearing by the general population could lead to relevant effects and consequences in many medical fields.

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“…Of these 39 patients, 7 increased benzodiazepine doses since the beginning of the pandemic. Another cross-sectional study conducted on 126 outpatients with AD found that patients with more severe forms of cognitive impairments had substantially lower scores on the Geriatric Depression Scale (GDS) than those suffering from mild cognitive impairment when measured at the end of the first lockdown [ 25 ]. These findings were explained by the fact that patients with more severe forms of NCD did not fully understand the context and the seriousness of the outbreak.…”

Section: Resultsmentioning

confidence: 99%

Systematic Review on the Mental Health and Treatment Impacts of COVID-19 on Neurocognitive Disorders

Dellazizzo

Léveillé

Landry

et al. 2021

JPM

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Objectives. The COVID-19 pandemic has had many public health impacts, especially on vulnerable individuals including adults with neurocognitive disorders (NCD). With increasing literature, this systematic literature review aimed to address the mental health effects of COVID-19 on people with NCD in addition to examine the impact of the pandemic on treatments/resources for NCD. Methods. A literature search was conducted in the electronic databases of PubMed, PsycINFO, Web of Science and Google Scholar. Studies were included so long as they assessed the mental health or therapeutic effects of COVID-19 on NCD. Results. Among the retrieved articles, 59 met eligibility criteria. First, the pandemic and resulting self-isolation led to many detrimental effects on psychological well-being. Exacerbation and relapses of neurocognitive and behavioral symptoms were observed, as well as emergences of new psychological symptoms (i.e., depression, anxiety). Second, therapeutic and community services for individuals suffering from NCD, such as social support services and outpatient clinics, were disrupted or reduced leading to postponed appointments and evaluations, as well as reduced access to medications. These issues were somewhat palliated with the growth of telemedicine. Conclusion. This systematic review highlights the extent of the effects of the pandemic, and the topics addressed should be taken into consideration by healthcare practitioners, institutions, and policymakers to ensure that proper measures are employed to protect this population from additional harm.

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Awareness of the COVID-19 Outbreak and Resultant Depressive Tendencies in Patients with Severe Alzheimer’s Disease

Cited by 17 publications

References 6 publications

Dementia wellbeing and COVID‐19: Review and expert consensus on current research and knowledge gaps

Dementia wellbeing and COVID‐19: Review and expert consensus on current research and knowledge gaps

Is a Mask That Covers the Mouth and Nose Free from Undesirable Side Effects in Everyday Use and Free of Potential Hazards?

Systematic Review on the Mental Health and Treatment Impacts of COVID-19 on Neurocognitive Disorders

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