Awareness, Willingness, and Perceived Efficacy of Pre-exposure Prophylaxis among Adolescent Sexual Minority Males

Gordián-Arroyo, Alvin; Garofalo, Robert; Kuhns, Lisa M.; Pearson, Cynthia; Bruce, Josh; Batey, D. Scott; Radix, Asa; Belkind, Uri; Hidalgo, Marco A.; Hirshfield, Sabina; Schrimshaw, Eric W.; Schnall, Rebecca

doi:10.1007/s11524-020-00447-5

Cited by 20 publications

(7 citation statements)

References 22 publications

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“…This willingness is higher than the levels of willingness found by other researches among key and priority populations; 46.5% by Lee, Chang et al, (2017), 55% by Holloway et al, (2017) among MSM in California, and 57.6% found by Ferrer et al, (2016) among MSM in Spain [ 9 , 11 , 12 ]. Our result is however close to that found by Peng, Cao et al, (2019) at 84.9% [ 13 ] and by Ssuna et al, in a fishing community in Uganda at 80.6% [ 14 ] but lower than the one found among adolescents (13–18 years) where it was 90.4% [ 10 ]. This variation could be due to inherent differences in attitudes and knowledge of the populations studied and their settings with majority being resource rich settings.…”

Section: Discussionsupporting

confidence: 87%

Factors associated with willingness to take Pre-Exposure Prophylaxis (PrEP) among high-risk adolescent boys and young men in Masese fishing community, Uganda

Agwang

Nangendo

Nabikande

et al. 2023

PLOS Glob Public Health

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Pre-Exposure Prophylaxis (PrEP) is a known HIV prevention strategy for high-risk populations however, some high-risk communities have not yet fully embraced it. We sought to determine willingness to take PrEP and the associated factors among high-risk adolescent boys and young men (ABYM) in Masese fishing community, Jinja district, Eastern Uganda. We conducted a cross-sectional study, between October and November 2020, using a semi-structured questionnaire among ABYM aged 10–24 years in Masese fishing community, Eastern Uganda. We surveyed 479 participants, who had two or more sexual partners with inconsistent or no condom use. We carried out modified Poisson regression analysis to determine factors associated with willingness to take PrEP.Of 479 high-risk ABYM, 86.4% (n = 414) were willing to take PrEP. Confidence in PrEP safety (adj.PR = 1.56; 95%CI: 1.55, 2.24), availability of PrEP in areas easily accessible by ABYM (adj.PR = 1.40; 95%CI: 1.25, 1.57), and perceiving oneself as being at a very high risk of HIV infection (adj.PR = 1.11; 95%CI: 1.03, 1.20) were positively associated with willingness to take PrEP. On the other hand, being unmarried (adj.PR = 0.92; 95%CI: 0.87, 0.98) and earning more than USD 27 a month (adj.PR = 0.92; 95%CI: 0.87, 0.97) were negatively associated with willingness to take PrEP. There was high willingness to take PrEP among adolescent boys and young men in Masese fishing community. Confidence in PrEP safety, access to PrEP in their community and self-perception to be at high risk for HIV acquisition had a positive bearing on willingness to take PrEP while being unmarried and earning more than USD27 had a negative bearing on willingness to take PrEP. These findings suggest a need for target-specific interventions for unmarried men and those earning >USD27.

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Section: Discussionsupporting

confidence: 87%

Factors associated with willingness to take Pre-Exposure Prophylaxis (PrEP) among high-risk adolescent boys and young men in Masese fishing community, Uganda

Agwang

Nangendo

Nabikande

et al. 2023

PLOS Glob Public Health

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“…First, there were those that were based in an educational institution (high school or university), included people of all genders and sexual orientations, and focused on contraception and STIs [ 27 - 29 , 41 , 42 ]. The second group was most commonly recruited from youth centers or sexual health clinics, focused exclusively on MSM, and had a clear focus on STI prevention and management [ 30 , 32 , 34 , 35 , 37 , 43 , 44 ].…”

Section: Resultsmentioning

confidence: 99%

Using Video Games to Improve the Sexual Health of Young People Aged 15 to 25 Years: Rapid Review

Vega¹,

Eleftheriou²,

Graham³

2022

JMIR Serious Games

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Background Sexually transmitted infections and unintended pregnancies among young people remain public health concerns in many countries. To date, interventions that address these concerns have had limited success. Serious games are increasingly being used as educational tools in health and professional public education. Although acknowledged as having great potential, few studies have evaluated the use of serious games in sexual health education among young people, and to date, there have been no published reviews of these studies. Objective This study aims to assess the effects of video game–based sexual health interventions for risky sexual behavior in young people aged between 15 and 25 years. Methods A rapid review of randomized controlled trials and quasi–randomized controlled trials was performed. The search included the following bibliographic databases: Cochrane Central Register of Controlled Trials, Embase, MEDLINE, PsycINFO, and Scopus. A total of 2 reviewers independently screened 50% (35/70) of the retrieved articles during the full-text screening phase. Results From a total of 459 identified citations, after removing duplicates, 327 (71.2%) articles were deemed eligible for title and abstract screening. Of the 327 articles, 70 (21.4%) full texts were screened, from which 10 (3.1%) articles (evaluating 11 different games) were included in the review. The findings highlighted the considerable diversity in video game–based interventions and assessed sexual health outcomes. Although there were some promising findings in outcome studies using game-based interventions, the results across studies were mixed. Conclusions Although game interventions for sexual health have been in existence for almost three decades, relatively few studies have evaluated them, and the results of previous outcome studies have been mixed. Moreover, there is little clarity regarding which specific elements of a game facilitate positive outcomes. We provide recommendations for future researchers developing video game–based interventions to improve sexual health in young people.

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“…This is contrary to findings especially from high-income countries, that have highlighted high interest of MSM in PrEP. 24,25 Myths and misconceptions about PrEP and other attributes of PrEP such as the daily dosing and routine screening and medication monitoring may affect interest and willingness in PrEP among these populations. 8,11,26,27 However, it is not clear why lack of interest was highest among MSM, considering the high risk of transmission associated with anal sex, particularly receptive anal intercourse.…”

Section: Discussionmentioning

confidence: 99%

Barriers to the uptake of oral pre-exposure prophylaxis among young key populations in Nigeria

Olakunde,

Ujam,

Ndukwe

et al. 2023

Int J STD AIDS

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Background Young key populations (YKP) contribute to the burden of HIV in Nigeria and are a priority population for oral pre-exposure prophylaxis (PrEP). However, their uptake of PrEP remains low. We assessed the main barriers to PrEP uptake and the variation among YKP (15–24 years) in Nigeria. Methods This study was a secondary data analysis of the 2020 Integrated Biological & Behavioural Surveillance Survey conducted among key populations (KP), including female sex workers (FSW), men who have sex with men (MSM), people who inject drugs (PWID), and transgender people (TG), in 12 states in Nigeria. A closed-ended question asking the main reason for not taking PrEP among KP who had never taken PrEP was included in the surveillance questionnaire. We collapsed the responses into six barrier themes. Using multinomial logistic regression analysis, we examined the association between the barriers (dependent variable) and KP group (independent variable), controlling for age, educational attainment, religion, marital status, employment status, and geopolitical zone. Results A total of 1776 YKP were included in this study. The most cited barriers by KP group were: lack of access (28.3%) and fear of side effects (28.3%) by FSW; lack of interest (37.1%) by MSM; low risk perception (65.5%) by PWID; and lack of access (34.4%) by TG. The odds of reporting fear of side effects, lack of access, lack of interest, and nonspecific/others reasons were significantly different by KP group. Conclusions The barriers limiting the uptake of PrEP among YKP vary by KP group. Our results highlight the need for KP-specific interventions to improve the uptake of PrEP among YKP in Nigeria.

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Awareness, Willingness, and Perceived Efficacy of Pre-exposure Prophylaxis among Adolescent Sexual Minority Males

Cited by 20 publications

References 22 publications

Factors associated with willingness to take Pre-Exposure Prophylaxis (PrEP) among high-risk adolescent boys and young men in Masese fishing community, Uganda

Factors associated with willingness to take Pre-Exposure Prophylaxis (PrEP) among high-risk adolescent boys and young men in Masese fishing community, Uganda

Using Video Games to Improve the Sexual Health of Young People Aged 15 to 25 Years: Rapid Review

Barriers to the uptake of oral pre-exposure prophylaxis among young key populations in Nigeria

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