Axial Psoriatic Arthritis

Gladman, Dafna D.

doi:10.1007/s11926-021-00999-8

Cited by 24 publications

(5 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4 The terminology used to describe axial involvement in PsA has been diverse: psoriatic spondylitis, psoriatic SpA and axial PsA, among others. [5][6][7] Moreover, there is no consensus on a definition of axial involvement in PsA. 8 Whether axSpA and axial PsA represent the same or different disorders remains controversial.…”

Section: Rmd Open Rmd Open Rmd Openmentioning

confidence: 99%

Characterisation of patients with axial psoriatic arthritis and patients with axial spondyloarthritis and concomitant psoriasis in the SCQM registry

Ciurea,

Götschi,

Kissling

et al. 2023

RMD Open

View full text Add to dashboard Cite

BackgroundWithin the spectrum of spondyloarthritides, axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) present with overlapping features. Axial involvement in PsA (axial PsA) is treated according to recommendations for axSpA, as specific studies in axial PsA are scarce. We compared characteristics of patients with axSpA (particularly of patients with axSpA and concomitant psoriasis (pso)) with those of patients with axial PsA.MethodsPatients with axSpA and PsA in the Swiss Clinical Quality Management (SCQM) registry were included if information on pso and axial involvement was available. Patients with AxSpA were stratified by axSpA with and without pso (axSpA±pso) and patients with PsA were stratified to axial PsA or strictly peripheral PsA.ResultsPrevious or current psoriasis was observed in 479/4489 patients with axSpA (10.7%). Of 2631 patients with PsA, 1153 (43.8%) presented with axial involvement (opinion of the treating rheumatologist). Compared with patients with axSpA+pso, patients with axial PsA were older at symptom onset and at inclusion in SCQM, were less frequently HLA-B27 positive, had back pain less frequently and a higher prevalence of dactylitis and peripheral arthritis. A positive family history of pso or PsA was more frequent in axial PsA, while a positive family history of axSpA was more frequent in patients with axSpA+pso. Disease activity, function and mobility were comparable in axSpA+pso versus axial PsA.ConclusionPatients with axial PsA differ from patients with axSpA+pso in important demographic and clinical characteristics, and genetically, but present with a comparable disease burden. Treatment studies specifically dedicated to axial PsA seem warranted.

show abstract

Section: Rmd Open Rmd Open Rmd Openmentioning

confidence: 99%

Characterisation of patients with axial psoriatic arthritis and patients with axial spondyloarthritis and concomitant psoriasis in the SCQM registry

Ciurea,

Götschi,

Kissling

et al. 2023

RMD Open

View full text Add to dashboard Cite

show abstract

“…It is also important to distinguish between the two major arthritis patterns in patients with suspected PsA—peripheral and/or axial—since the type of arthritis can impact patient disease state and treatment strategy. The majority of patients with PsA experience peripheral joint involvement, and approximately 25–70% of patients have axial involvement [ 47 , 48 ], depending on the definition of axial disease applied. To screen for peripheral arthritis, practitioners should evaluate patients for swelling and tenderness, which can be indicative of synovitis and inflammation, as well as commonly affected joints, such as feet and hands, knees, wrists, ankles, and shoulders [ 24 ].…”

Section: Key Clinical Features For Differential Diagnosis Of Psamentioning

confidence: 99%

Differentiating Psoriatic Arthritis from Osteoarthritis and Rheumatoid Arthritis: A Narrative Review and Guide for Advanced Practice Providers

Saalfeld¹,

Mixon²,

Zelie

et al. 2021

Rheumatol Ther

View full text Add to dashboard Cite

Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects multiple organ systems and is characterized by skin and joint manifestations. PsA is frequently undiagnosed and/or misdiagnosed, especially because of the similarities in clinical presentation shared with other arthritic diseases, including rheumatoid arthritis (RA) and osteoarthritis (OA). An accurate and timely diagnosis of PsA is crucial to prevent delays in optimal treatment, which can lead to irreversible joint damage and increased functional disability. Patients are usually seen by a number of different healthcare providers on their path to a diagnosis of PsA, including advanced practice providers (APPs). This review provides a comprehensive overview of the characteristic features that can be used to facilitate the differentiation of PsA from RA and OA. Detailed information on clinical manifestations, biomarkers, radiologic features, and therapeutic recommendations for PsA included here can be applied in routine clinical settings to provide APPs with the confidence and knowledge to recognize and refer patients more accurately to rheumatologists for management of patients with PsA.

show abstract

“…Enthesitis is present also in PsA and represents a distinguishing feature of the disease, being present in 35% of PsA patients 10 . Axial symptoms associated with back stiffness and pain that improves with movement, may occur in up to 50% of patients with PsA 11 . Fibromyalgia (FM), a non-in ammatory chronic musculoskeletal disease characterized by chronic widespread pain and fatigue, has a prevalence estimated at around 2% with the majority of patients being female 12 .…”

Section: Introductionmentioning

confidence: 99%

Performance of standardized patient reported outcomes developed for spondyloarthritis in primary and concomitant forms of fibromyalgia

Tsiami,

Dukatz,

Gkelaki

et al. 2024

Preprint

View full text Add to dashboard Cite

Background. In spondyloarthritides (SpA) and fibromyalgia (FM), patients suffer from generalized pain. The impact of FM on PRO validated in SpA has not been systematically studied. Objective. Study the performance of PROs developed for SpA in patients with primary (p) FM without chronic inflammatory-rheumatic disease vs. SpA without and with concomitant (c) FM. Methods. Patients with pFM, axSpA or PsA and indication for treatment adaptation were prospectively included. Standardized PROs were assessed: BASDAI, ASDAS-CRP, DAPSA, patient´s global assessment, BASFI, LEI, MASES, SPARCC Enthesitis Score and FIQ. Results. 300 patients were included (100/diagnosis). More males were found in axSpA vs. PsA and pFM group (67, 33 and 2/100, respectively), while 12 axSpA (axSpA+) and 16 PsA (PsA+) patients had cFM. pFM patients showed significantly higher scores in all assessments vs. axSpA or PsA, with exception of ASDAS-CRP (3.3±0.6 in FM vs. 3.1±1.0 in axSpA) and duration of low lumbar morning stiffness. Similar results were also found in the subanalysis of female patients only. In addition, patients with axSpA+ or PsA+ showed no differences to patients with pFM, while significantly higher scores were found for FM, axSpA+ and PsA+ for almost all FIQ items compared to axSpA- or PsA-. Conclusions. PROs originally developed for axSpA or PsA need to be interpreted differently in the presence or absence of cFM. ASDAS-CRP and duration of lumbar morning stiffness were not affected by cFM. FM-specific questionnaires also showed high scores in patients with SpA with cFM but not in those without.

show abstract

Axial Psoriatic Arthritis

Cited by 24 publications

References 32 publications

Characterisation of patients with axial psoriatic arthritis and patients with axial spondyloarthritis and concomitant psoriasis in the SCQM registry

Characterisation of patients with axial psoriatic arthritis and patients with axial spondyloarthritis and concomitant psoriasis in the SCQM registry

Differentiating Psoriatic Arthritis from Osteoarthritis and Rheumatoid Arthritis: A Narrative Review and Guide for Advanced Practice Providers

Performance of standardized patient reported outcomes developed for spondyloarthritis in primary and concomitant forms of fibromyalgia

Contact Info

Product

Resources

About