2013
DOI: 10.1111/tbj.12205
|View full text |Cite
|
Sign up to set email alerts
|

Axillary Lymph Node Status and Prognosis in Multifocal and Multicentric Breast Carcinoma

Abstract: According to tumor-node-metastasis classification, tumor size should be based only on the largest tumor for multifocal and multicentric (MFMC) carcinomas. We estimated tumor size of MFMC carcinoma using either largest dimension of the largest tumor (dominant tumor size) or sum of the largest dimension of all tumors (aggregate tumor size), and compared the risk of axillary lymph node metastasis and prognosis between MFMC and unifocal carcinoma. We retrospectively reviewed the file records of 3,616 patients with… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

1
13
1

Year Published

2014
2014
2023
2023

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 16 publications
(15 citation statements)
references
References 25 publications
1
13
1
Order By: Relevance
“…Multiple studies have demonstrated that aggregation of tumor foci may result in better prediction of nodal disease . On the other hand, a recent study by Duraker and Caynak found no difference in the incidence of node positivity when staging by aggregated tumor size versus largest tumor dimension in patients with MF/MC breast cancers .…”
Section: Discussionmentioning
confidence: 95%
“…Multiple studies have demonstrated that aggregation of tumor foci may result in better prediction of nodal disease . On the other hand, a recent study by Duraker and Caynak found no difference in the incidence of node positivity when staging by aggregated tumor size versus largest tumor dimension in patients with MF/MC breast cancers .…”
Section: Discussionmentioning
confidence: 95%
“…The axillary lymph node status is an important prognostic factor in patients with breast cancer . Up to now, there have been no appropriate methods to confirm the axillary lymph node status except for pathologic examination of axillary lymph nodes.…”
Section: Discussionmentioning
confidence: 99%
“…Epithelial breast tissue tumorigenesis may arise from a single or from several distinct sites within the same breast, leading to multifocality, defined as multiple simultaneous ipsilateral and synchronous breast carcinomas [ 1 ]. Such a cancer presentation appears to have a poor prognosis in breast cancer patients, with a greater probability of relapse and shorter survival than in women with unifocal tumors [ 2 , 3 , 4 , 5 ]. Mechanisms underlying multifocality remain unclear.…”
Section: Introductionmentioning
confidence: 99%