1994
DOI: 10.1073/pnas.91.20.9636
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Axotomy induces the expression of vasopressin receptors in cranial and spinal motor nuclei in the adult rat.

Abstract: 8-L-Aine vasopressin ([Arg8]VP) receptors are expressed transiently in the rat facial nucleus during the perinatal period. Electrophysiological studies suggest that at least part of these receptors is located on facial motoneurones. In the present study we report that, in the adult rat, unilateral section of a facial nerve results In a massive and transient reexpression of [Arg8JVP receptors in the deeflerented facial nucleus. Data MATERIAL AND METHODS Animals and Surgery. Experiments were performed on adult… Show more

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Cited by 24 publications
(9 citation statements)
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“…Are pudendal motoneurons from adults also responsive to vasopressin and tachykinins? In adult male rats, pudendal motor nuclei contain vasopressin and tachykinin binding sites (Charlton and Helke, 1985;Tribollet et al, 1997), a fact that contrasts with what is found in other spinal motor nuclei and brainstem motor nuclei, in which these binding sites are detectable in neonate but not in adults (Quirion and Dam, 1986;Tribollet et al, 1991Tribollet et al, , 1994. This suggests that pudendal motoneurons of adults can be excited by vasopressin and tachykinins.…”
Section: Comparison With Nonpudendal Motoneuronscontrasting
confidence: 45%
“…Are pudendal motoneurons from adults also responsive to vasopressin and tachykinins? In adult male rats, pudendal motor nuclei contain vasopressin and tachykinin binding sites (Charlton and Helke, 1985;Tribollet et al, 1997), a fact that contrasts with what is found in other spinal motor nuclei and brainstem motor nuclei, in which these binding sites are detectable in neonate but not in adults (Quirion and Dam, 1986;Tribollet et al, 1991Tribollet et al, , 1994. This suggests that pudendal motoneurons of adults can be excited by vasopressin and tachykinins.…”
Section: Comparison With Nonpudendal Motoneuronscontrasting
confidence: 45%
“…This suggests that descending vasopressinergic projections may play a role in regulating somatic motor activity. The fact that vasopressin receptors are preferentially expressed in motoneurons early in development (Tribollet et al ., 1991; Liu et al ., 2003) and the fact that in adulthood these receptors are up‐regulated following lesion of motor axons (Tribollet et al ., 1994) further suggest that central vasopressin may be involved in the maturation and repair of motor networks.…”
Section: Resultsmentioning
confidence: 99%
“…Previous studies from our laboratory have shown that in the facial nucleus, another class of membrane receptors, vasopressin receptors, are transiently expressed during the perinatal period and are upregulated by axotomy, indicating that these receptors, in addition to enhancing facial motoneuron excitability (Raggenbass et al . 1991), may be involved in the establishment of neuromuscular connections during development and in their re‐establishment after nerve injury (Tribollet et al . 1991, 1994).…”
Section: Discussionmentioning
confidence: 99%